- Common Name: Diflucan®
- Drug Type: Antifungal
- Used For: Yeast and fungal infections
- Species: Dogs, Cats
- Administered: Tablets, Oral liquid
- How Dispensed: Prescription only
- Available Forms: 50 mg, 100 mg, 150 mg, 200 mg Tablets
- FDA Approved: No
Fluconazole is an antifungal drug effective against fungus and yeast. It is typically used for skin infections, fungus in the nailbeds, and more intense fungal infections including Blastomycosis and Histoplasmosis. It is related to Ketoconazole, but is able to more effectively cross the brain-blood barrier, making it more successful in treating fungal infections of the central nervous system. Fluconazole is also effective against ringworm, but is typically reserved for more serious infections.
Fluconazole has fewer side effects than most other antifungals.
How It Works
Fluconazole works by inhibiting production of the fungal cell wall. This causes the fungus to be structurally inadequate so that it leaks and dies.
Tablets should be kept in a tightly sealed container at room temperature. Oral liquids should be refrigerated and shaken before use.
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.
Side Effects and Drug Reactions
Fluconazole has been found to be very safe in pets, but not extensively researched. These side effects have been observed in humans on this drug:
- Allergic reaction (labored breathing, hives, etc)
- Skin rash
- Loss of appetite
- Dark urine or jaundice due to liver failure
- Pale tongue, gums, and nose
Please contact your veterinarian and stop use of Fluconazole if any of these reactions occur.
Fluconazole may react with these drugs:
- Amphotericin B
DO NOT GIVE FLUCONAZOLE TO PREGNANT PETS
USE CAUTION WHEN ADMINISTERING THIS DRUG TO DIABETIC PETS, LACTATING PETS, KIDNEY DISEASE, OR LIVER DISEASE
Help us make PetMD better
Was this article helpful?