Otomax for Dogs

What Is Otomax Used for in Dogs?

Otomax is the brand name for a prescription combination otic (ear) ointment that contains three active ingredients:  

• Clotrimazole 
• Betamethasone 
• Gentamicin 

This medication is used to treat external ear infections in dogs caused by susceptible strains of yeast (Malassezia pachydermatis) and bacteria susceptible to the antibiotic gentamicin. Otomax also reduces discomfort, redness, swelling, discharge, and odor, while treating the underlying infection.

Is Otomax FDA-Approved for Dogs? 

Yes, Otomax is FDA-approved for use in dogs for the treatment of otitis externa (outer ear infections).  

Speak with your veterinarian about whether Otomax is right for your pet. 

Otomax Considerations for Dogs

Before using Otomax, it is critical that your veterinarian examines your dog’s eardrum to ensure it is intact to avoid damage to the inner ear. This product should not be used in dogs with known perforation of eardrums. 

Your vet needs to perform tests of the ear discharge to determine if Otomax is the best choice for your dog’s ear infection. 

Otomax should not be used in pregnant dogs. 

How Does Otomax Work in Dogs?

Otomax contains three ingredients that work together to treat susceptible ear infections: 

• Gentamicin: an antibiotic active against several common pathogenic bacteria that infect the ear 
• Betamethasone: a steroid used to decrease inflammation in the ear canal 
• Clotrimazole: a broad-spectrum antifungal agent used to treat common yeast organisms 

If your dog’s ear infection does not improve after treatment with Otomax, the cause of the infection may be other microorganisms that are not susceptible to this medication. 

How Do You Give Otomax to Dogs?

Follow the directions on the drug label or as provided by your veterinarian. 

Otomax is administered directly into the infected ear canal twice daily for seven consecutive days. Your veterinarian will prescribe an appropriate number of drops to administer into each ear, which can vary based on your dog’s weight.  

1. Clean and dry your dog’s ears before administering. Your vet can advise whether you should air-dry your pup’s ears or gently wipe them dry with gauze or cotton balls, based on the severity of their condition. Your vet may clean the ears in the office and instill the first dose of Otomax there. 

2. If your pet has long hair, trim the area around the ears before giving your dog Otomax.  

3. Shake the bottle well before each use. 

4. Place the prescribed amount of drops into your dog’s ear.  

5. Gently massage the external ear canal to appropriately distribute the medication.  

6. Discontinue treatment after seven days. 

Administration of this medication beyond the recommended seven days may result in delayed wound healing. 

What Happens If You Miss a Dose of Otomax? 

Speak with your veterinarian about what to do if a dose is missed.  

Generally, your vet may instruct you to give it when you remember, or if it is almost time for your pet’s next dose, to skip the missed dose and resume your normal dosing schedule. 

Do not give extra or double doses. 

What Are the Side Effects of Otomax in Dogs?

Otomax has a wide safety margin and is well-tolerated in dogs.  

Rare side effects seen in a small number of geriatric dogs include:  

• Hearing loss (rare and usually temporary)   
• Head tilting and lack of coordination (signs of vestibular disease)  

If hearing loss or signs of vestibular disease are noted during treatment, immediately discontinue use of Otomax and call your veterinarian.  

Human Side Effects 

Humans should never take medication prescribed for pets, and pets should not be given medication prescribed for humans. Dosages often differ significantly. 

If you accidentally ingest a pet medication, seek medical attention or call Poison Control at 800-222-1222.  

Monitoring Your Pet 

No specific monitoring is required for this medication, but your veterinarian may recommend routine testing depending on your dog’s individual needs, other medications that may be prescribed, and/or the issue that initially caused your dog to be placed on this medication. 

When Should You Call Your Veterinarian? 

Contact your veterinarian if you see any of the following, or if you have additional questions or concerns about the use of Otomax: 

• Severe side effects occur  
• Your dog’s condition worsens or does not improve   
• You suspect an overdose  

What Happens If a Pet Overdoses on Otomax?

Overdosing on Otomax is not common, but sensitivity or allergic reactions can occur. 

If your pet is showing signs of hearing loss, head tilt, circling, or other signs of vestibular disease, contact your veterinarian immediately. 

If your dog accidentally ingests Otomax, seek veterinary care and observe your dog closely for: 

• Fluid retention (swelling) 
• Weight gain 
• Increased thirst and/or urination 

Prolonged use of Otomax or overdosage of Otomax can suppress your dog’s immune system, causing them to be more susceptible to infection.  

If you suspect an overdose, seek emergency veterinary care or contact an animal poison control center. Consultation fees may apply. 

• Pet Poison Helpline: 855-764-7661
• ASPCA Animal Poison Control: 888-426-4435 

How Should Otomax Be Stored for Dogs?

To store Otomax safely: 

• Always confirm storage requirements by reviewing the label.  
• Keep it in a safe, dry place at a temperature between 36–77 F (2–25 C).  
• Keep out of reach of children and pets.