Galliprant (Grapiprant) for Dogs
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If your dog has been diagnosed with osteoarthritis, your veterinarian may prescribe Galliprant to help manage pain and improve mobility. Here’s what pet parents should know about how Galliprant works, how to give it safely, and its possible side effects.
Key Takeaways
- Galliprant (grapiprant) is an FDA-approved prescription medication used to manage pain and inflammation caused by osteoarthritis in dogs.
- Galliprant is a new type of NSAID that targets pain differently from traditional anti-inflammatory medications.
- Galliprant is given once daily, with or without food, as directed by your veterinarian.
- Tell your veterinarian about your dog's medical history and any medications or supplements they are taking before starting Galliprant.
What Is Galliprant Used for in Dogs?
Galliprant (grapiprant) is an FDA-approved prescription nonsteroidal anti-inflammatory drug (NSAID) used to manage pain and inflammation caused by osteoarthritis in dogs.
Osteoarthritis develops when the protective cartilage inside a joint wears away, causing bones to rub together. This can make everyday activities such as walking, climbing stairs, jumping, or getting up after resting painful.
Galliprant doesn't cure osteoarthritis, but it can help reduce pain, improve mobility, and make your dog more comfortable.
Galliprant Considerations for Dogs
Before starting Galliprant, tell your veterinarian about your dog's health history and any medications or supplements they take. They can help determine whether Galliprant is a safe choice for your dog.
Do not use Galliprant in dogs allergic to grapiprant
Safety has not been established in:
- Dogs younger than 9 months
- Dogs weighing less than 8 pounds
- Breeding, pregnant, or nursing dogs
Use with caution in:
- Dogs with heart disease
- Dogs with poor kidney or liver function
- Dogs with gastrointestinal disease
Tell your veterinarian if your dog:
- Has the MDR1 gene mutation
- Is given any medications, vitamins, or supplements
Dogs with the MDR1 mutation may process Galliprant differently, so your veterinarian may recommend a lower dose.
How Does Galliprant Work in Dogs?
Galliprant is a newer type of NSAID that targets pain differently from traditional anti-inflammatory medications. It blocks a receptor involved in pain and inflammation while having less effect on the stomach, kidneys, blood vessels, and normal blood clotting.
How Do You Give Galliprant to Dogs?
Check instructions on the label and give Galliprant exactly as directed by your veterinarian.
When giving Galliprant, remember:
- Galliprant is given once daily, with or without food.
- If your dog is reluctant to take tablets, ask your veterinarian whether hiding the medication in a pill wrap or pill pouch, such as Greenies Pill Pockets, is appropriate.
- Your veterinarian will prescribe the lowest effective dose based on your dog's needs.
What Happens If You Miss a Dose of Galliprant?
Give the missed dose as soon as you remember unless it's almost time for the next dose. Never give two doses at the same time.
What Are the Side Effects of Galliprant in Dogs?
Common side effects of Galliprant in dogs may include:
- Vomiting and diarrhea
- Lack of appetite
- Lethargy
- Soft, watery, or bloody stools
Contact your veterinarian if these side effects are severe, don't improve, or get worse.
Human Side Effects
Galliprant is not intended for human use. Due to possible side effects, humans should never use medicine dispensed for their pets, and pets should not be given any medicine dispensed for a human’s use.
If someone accidentally swallows the medication, call your physician or the Poison Control Center at 1-800-222-1222.
Monitoring Your Dog
Your veterinarian may recommend periodic bloodwork, especially if your dog takes Galliprant long term. Additional monitoring may be recommended based on your dog's health and any other medications they take.
When Should You Call Your Veterinarian?
Call your veterinarian if you see any of the following or if you have additional questions or concerns about the use of Galliprant:
- Severe side effects occur
- Your pet’s condition worsens or does not improve
- You see or suspect an overdose
What Happens If a Dog Overdoses on Galliprant?
An overdose of Galliprant may cause vomiting, decreased appetite, diarrhea, or changes in liver values and blood protein levels.
If you think your dog received too much Galliprant, contact your veterinarian, seek emergency veterinary care, or call an animal poison control center immediately.
- Pet Poison Helpline: (855) 764-7661
- ASPCA Animal Poison Control: (888) 426-4435
How To Store Galliprant for Dogs
Keep these tips in mind when storing your dog’s Galliprant:
- Store at room temperature at or below 86 F (30 C).
- Keep the container tightly closed.
- Protect from moisture and light.
- Keep out of reach of children and pets.
Galliprant for Dogs FAQs
How long can a dog stay on Galliprant?
Many dogs take Galliprant long term to help manage osteoarthritis. Your veterinarian will determine the lowest effective dose and monitor your dog over time.
How long does it take for Galliprant to work for a dog?
Many dogs begin showing improvement within a few days, although some may take up to a month to experience the full benefit.
Does Galliprant make a dog sleepy?
Galliprant doesn't typically cause sleepiness, but some dogs may seem more relaxed and may rest better when taking Galliprant because their pain level is much improved. Contact your veterinarian if your dog becomes unusually tired while taking the medication.
Can Galliprant be taken with other pain medications?
It depends on the medication. Do not give Galliprant with another NSAID or a corticosteroid unless your veterinarian specifically instructs you to do so, as combining these medications can increase the risk of side effects. If your dog needs additional pain relief, your veterinarian can recommend medications that are safe to use with Galliprant.
No vet writer or qualified reviewer has received any compensation from the manufacturer of the medication as part of creating this article. All content is sourced from public references or the manufacturer.
