The World’s First Clinically Studied Probiotic Soft Chew for Dogs

Published Jun. 1, 2026
Probiotics support health gut function in dogs.

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This article was written exclusively by PetLabCo. as promotional content and is published on PetMD.

If you’ve had to struggle with your dog’s occasional loose stools, gas, or digestive issues in the past, then you’ve likely considered their gut health. But here is what most owners miss: the microbiome’s impact goes far beyond just digestion… 

Science now shows that an imbalanced gut is often the “hidden culprit” behind seasonal allergies, yeast growth, low energy and even behavior. If your dog won’t stop licking their paws, scratching or shaking their head, then the root cause of the issue could stem from poor gut health. 

Read on to discover why over 2.2 million dog owners are turning to PetLabCo.®‘s Probiotic Chews to support their dog’s gut health. 

With over 10 million tubs sold, PetLabCo.®‘s Probiotic Chews are now America’s #1 Dog Probiotic Soft Chew. But what really sets them apart is their commitment to scientific research.  
 
PetLabCo.® achieved a rare milestone in pet wellness by conducting a double-blind, placebo-controlled clinical study on the final formula. With results validated in a peer-reviewed scientific journal, these soft chews offer a level of clinical transparency that is virtually unheard of in the pet supplement industry. Making them the world’s first clinically studied probiotic soft chew for dogs. 

Developed in America by leading pet nutritionist Dr. Greg Sunvold to target the root cause of gut imbalance rather than masking the signs, the formula is now helping millions of dog owners rethink how they care for their dog’s gut health. 

Key Takeaways

  • PetLabCo.® Probiotic Chews are America's #1 Dog Probiotic Soft Chew and the world's first clinically studied probiotic soft chew for dogs.
  • The formula was developed with Dr. Greg Sunvold, one of the world's leading pet nutritionists.
  • The soft chews support five of the most common everyday concerns in dogs: gut health, seasonal allergy discomfort, grass eating, yeast-related signs, and seasonal itching.
  • In a 90-day customer survey, 89% of dog parents reported seeing results and 82% saw less itching, paw licking, and head shaking.
  • The clinical study is peer-reviewed by independent scientists and published in a scientific journal, not just a marketing claim.

Why Your Dog's Gut Matters More Than You Think

You may not think of your dog's gut as the command center for their health. But it is. An estimated 80% of a dog's immune system lives in their gut. When the balance of bacteria tips in the wrong direction, the effects can show up all over the body: scratching, yeasty ears and paws, occasional loose stools, and yes, a sudden fascination with grass

Think of the gut as the ecosystem that keeps everything else working smoothly: digestive function, immune response, skin comfort, even behavior. When it's thriving, the whole dog tends to follow. When it's off, signs tend to show up in places pet parents don't always connect back to the gut. 

That's exactly the thinking behind PetLabCo.® Probiotic Chews, a daily soft chew built to support the foundation your dog's everyday wellness depends on. 

5 Signs Your Dog's Gut Could Use Support

If any of these sound familiar, your dog may benefit from daily probiotic support. 

1. Occasional loose stools, gas, or inconsistent digestive function 

One of the clearest signs of an imbalanced gut is an imbalanced stool. Soft poops, gas, bloating, or imbalanced digestive function that varies wildly from one day to the next are all signals the gut flora could use rebalancing. Digestive health support is one of the most common reasons pet parents turn to probiotics in the first place. 

2. Seasonal allergy discomfort 

Because so much of the immune system lives in the gut, a healthy microbiome can support a more balanced response to seasonal allergy triggers like pollen, grass, and house allergens, which often show up as head shaking, ear irritation, and paw chewing. 

3. Grass eating 

Grass eating in dogs is common and not always a red flag, but it can sometimes reflect a gut imbalance or a search for fiber. Supporting healthy digestive function with prebiotics and probiotics may help curb the behavior, especially when paired with other signs of occasional tummy trouble. 

4. Yeasty paws, ears, or skin 

That musty, "corn chip" smell from the paws? Brown-stained fur where your dog has been licking? Those are often signs of a yeast imbalance. A healthy gut helps support healthy yeast levels from the inside out. 

5. Seasonal itching, paw licking, or head shaking 

When dogs are uncomfortable, they tell us through scratching, licking, and shaking. For many dogs, gut health is a key piece of the puzzle alongside any vet-recommended itch support plan. 

PetLabCo.® Probiotic Chews were specifically formulated to support all five of these everyday concerns in a daily soft chew, which is exactly why so many pet parents make them part of their dog's routine. 

What to Look for in a Dog Probiotic (And Why Most Fall Short)

Walk through the dog probiotics aisle and you'll find dozens of options. Here's what separates the best from the rest: 

  • Published clinical research, not just testimonials, marketing claims or borrowed clinical study claims on the single ingredients. Look for peer-reviewed studies on the full formula. 

  • A complete prebiotic + probiotic + postbiotic formula. Probiotics alone can't do the job; they need prebiotic fiber to thrive and postbiotics to deliver benefits. 

  • Spore-forming probiotic strains that can survive stomach acid and reach the gut alive. Many cheaper probiotics don't. 

  • Expert formulation from a qualified pet nutritionist or veterinary scientist. 

  • Quality you can trust, like manufacturing in the USA, using domestic and globally sourced ingredients, third-party testing for potency and quality, and NASC certified brands for meeting the industry's rigorous standards for animal supplements. 

  • A format your dog will actually eat. A probiotic that ends up under the couch isn't doing anyone any good.  

That's a high bar to clear. PetLabCo.'s Probiotic Chews check every box, and they're the first probiotic soft chew for dogs with published, peer-reviewed clinical research to back it up1

The Science Behind PetLabCo.Ⓡ’s Probiotic Chews

PetLabCo.®'s Probiotic Chews aren't just another supplement. They're a category-defining product: America's #1 Dog Probiotic Soft Chew2, with more than 2.2 million customers and over 10 million tubs sold to date. 

Here's what sets them apart. 

A formula built with one of the world's leading pet nutritionists 

PetLabCo.® partnered with Dr. Greg Sunvold, one of the world's most respected pet nutritionists, to develop the formula. Dr. Sunvold has spent decades researching companion-animal nutrition, and that expertise shaped every ingredient in the soft chew. 

The world's first clinically studied probiotic soft chew for dogs

Plenty of probiotics say they "work." PetLabCo.® put theirs to the test. A 29-day clinical study showed that daily use of Probiotic Chews significantly enhances beneficial gut bacteria and supports a balanced inflammatory response in the gut. The results were published in a peer-reviewed scientific journal and reviewed by independent scientists, a level of transparency that's rare in the pet supplement category. 

Research-backed active ingredients 

PetLabCo.® Probiotic Chews deliver a complete prebiotic + probiotic + postbiotic system. And that matters, because each piece does a different job: 

  • Probiotics are the beneficial bacteria themselves. 

  • Prebiotics are the fiber those bacteria feed on to thrive. 

  • Postbiotics are the beneficial compounds those bacteria produce once they're flourishing. 

Most probiotics on the market deliver only one piece of this puzzle. PetLabCo.® delivers all three, in every 4-gram pork-flavored soft chew: 

  • 3 billion CFU of a spore-forming probiotic blend (Bacillus coagulans, B. clausii, B. subtilis): strains chosen for their ability to better survive stomach acid and reach the gut alive. 

  • 100 mg of Fructooligosaccharides (FOS): a prebiotic fiber that feeds beneficial bacteria. 

  • 100 mg of Galactooligosaccharides (GOS): a second prebiotic that supports gut barrier integrity. 

  • 75 mg of a synergistic postbiotic yeast blend (Saccharomyces cerevisiae, Cyberlindnera jadinii) to support gut balance, immune function, and digestive function. 

And because they're pork-flavored soft chews, most dogs think they're getting a reward. 

The Real Results Dog Parents Are Seeing

In a 90-day subscriber survey of PetLabCo.® customers, pet parents reported3

  • 89% saw results 

  • 88% saw better gut health 

  • 86% saw better digestion 

  • 82% saw less itching, paw licking, and head shaking 

  • 87% said they would recommend the chews 

  • 92% said giving Probiotic Chews to their dog was easy from day one 

Those are the kinds of numbers that come from a formula built on science and refined with real-world feedback from millions of dogs. 

How to Give Your Dog PetLabCo.® Probiotic Chews

The soft chews are suitable for all breeds and for dogs and puppies 12 weeks and older. Daily amount is based on your dog's weight: 

  • Small dogs (under 25 lbs): 1 soft chew daily 

  • Medium dogs (25–75 lbs): 2 soft chews daily 

  • Large dogs (over 75 lbs): 3 soft chews daily 

Give daily at a time that works best for your dog. Results build over time, and most pet parents notice meaningful changes between the 60- and 90-day mark. Setting up Autoship on Chewy is an easy way to keep the routine consistent (and save on every order). 

Probiotic Chew FAQs

How long before I see results from PetLabCo.® Probiotic Chews?

Every dog is different, but most pet parents start noticing changes (firmer stools, less seasonal itching, more comfortable digestive function) somewhere between 30 and 90 days of daily use. In PetLabCo.®'s 90-day customer survey, 89% of dog parents reported seeing results3

Are PetLabCo.® Probiotic Chews safe for puppies?

The chews are suitable for puppies 12 weeks and older, as well as adult and senior dogs of all breeds. As always, check with your vet before starting any new supplement, especially if your dog is pregnant, nursing, or on medication. 

Can I give Probiotic Chews to my dog every day?

Yes. They're formulated for daily, long-term use. Consistency is the single most important factor in getting the most out of any probiotic. 

How are Probiotic Chews different from probiotic powders?

Powders can be messy, easy to miscount, and easy to skip. Soft chews are pre-measured, ready to give, and most dogs think they're a reward. In PetLabCo.®’s survey, 89% of dogs ate the soft chew happily on day one3

Should I still talk to my vet?

Absolutely. Probiotics aren't a replacement for veterinary care. If your dog is dealing with persistent itching, chronic digestive issues, or signs of infection, connect with a vet to rule out underlying conditions first. ShapeReady to join the 2 million+ dog parents already seeing results? 

Shop PetLab Co. Probiotic Chews on Chewy

References

  1. A 29-day clinical study showed using Probiotic Chew daily enhances beneficial gut bacteria. 

  1. YTD 2026 (as of May 2026) PetLabCo.® Probiotic Chew is #1 selling Probiotic Soft Chew in the Dog Probiotics Supplements Category on Amazon. 

  1. Based on a survey of PetLabCo. subscribers who reported using Probiotic Chews daily or almost daily for 90+ days. Results reflect customer feedback collected in September 2025 (¹n=307; ²n=249, based on subscribers whose dogs itched, paw licked or shook their head; ³n=139, based on subscribers whose dogs had occasional digestive issues; ⁴n=224, based on subscribers who wanted better gut health; ⁵n=298). 

  2. Clinical study: Sunvold, G.D. et al. A Spore-Forming Probiotic Blend for Canine Gut Health. Published in MDPI Pets, peer-reviewed by independent scientists. 

References


WRITTEN BY

Israel Swann

Sponsored Content Author


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