PetMD Editorial
Written by:
PetMD Editorial
Published: December 21, 2012

Drug Info

  • Common Name: Previcox
  • Generics: No generics available at this time
  • Drug Type: Non-steroidal anti-inflammatory drug (NSAID) in a class called COX-2 inhibitors
  • Used For: Pain and inflammation associated with osteoarthritis
  • Species: Dogs
  • Administered: Tablets
  • How Dispensed: Prescription Only
  • Available Forms: 57mg & 227mg Tablets
  • FDA Approved: Yes, for dogs


Firocoxib is used in dogs for pain and inflammation associated with osteoarthritis. Firocoxib is also used to help control postoperative pain and inflammation associated with soft-tissue and orthopedic surgery.

Dosage and Administration

Firocoxib (Previcox) should be given according to your veterinarian’s instructions. Do not change the way you give Firocoxib without speaking with your veterinarian first.

The recommended dose of Firocoxib for oral administration in dogs is 2.27mg/lb (5.0mg/kg) body weight once daily as needed. Previcox is a chewable tablet that can be given orally or given with food to help reduce the changes of an upset stomach.

Missed Dose?

If a dose of Firocoxib (Previcox) is missed, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Possible Side Effects

Firocoxib (Previcox) like other NSAIDs may cause some side effects. The most common side effects of Firocoxib involve digestive issues such as vomiting and decrease appetite. Other possible side effects of Firocoxib include:

  • Change in bowl movements (diarrhea, or black, tarry or bloody stools)
  • Change in behavior (decreased or increased activity level, incoordination, seizure, or aggression)
  • Jaundice (yellowing of gums, skin or whites of eyes)
  • Increase water consumption or urination changes (frequency, color, or smell)
  • Skin irritation (redness, scabs, or scratching)
  • Unexpected weight loss

It is important to stop the medication and immediately contact your veterinarian if you think your dog has any medical problems or side effects while taking Firocoxib (Previcox).


Firocoxib (Previcox) is for use in dogs only. Firocoxib should not be given to dogs that are hypersensitive to NSAIDs. Firocoxib should not be given with any other NSAIDs, including: Carprofen (Rimadyl), Meloxicam (Metacam), Etodolac (Etogesic), Deracoxib (Deramaxx), Aspirin.

Do not use in dogs that weigh less than 12.5 pounds. The safe use of Firocoxib (Previcox) in pregnant, lactating or breeding dogs has not been evaluated.

Dogs that are dehydrated, on concomitant diuretic therapy, or those with existing renal, cardiovascular, and/or hepatic dysfunction are at a greater risk for experiencing adverse events.

Use of Firocoxib (Previcox) at doses above the recommended dose in puppies less than seven months of age has been associated with serious adverse reaction, including death.


Store at room temperature, store between 59 and 86 Degrees Fahrenheit. Brief periods up to 104 Degrees Fahrenheit are permitted. Keep out of reach of pets and children.

Drug Interactions

Firocoxib (Previcox) should not be given with other NSAIDs or corticosteroids (e.g., prednisone, cortisone, dexamethasone or tramcinolone).

Signs of Toxicity/Overdose

Overdose of Firocoxib (Previcox) may cause:

  • Loss of appetite
  • Vomiting
  • Diarrhea
  • Dark or tarry stool
  • Increased thirst
  • Increase urination
  • Pale gums
  • Jaundice
  • Lethargy
  • Fast or heavy breathing
  • Incoordination
  • Seizures
  • Behavior changes           

If you suspect or know you dog has had an overdose, it could be fatal so please contact your veterinarian, an emergency vet clinic, or the Pet Poison Helpline at (855) 213-6680 immediately.

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