- Drug Name: Benazepril
- Common Name: Lotensen®, Fortekor®
- Drug Type: ACE Inhibitor
- Used For: Heart failure, kidney failure
- Species: Dogs, Cats
- Administered: Tablets, Oral liquid
- How Dispensed: Prescription only
- Available Forms: 5 mg, 10 mg, 20 mg and 40 mg tablets
- FDA Approved: No
Benazepril is used to treat minor to severe heart failure, high blood pressure, or loss of protein in the kidney due to some kidney diseases. It lowers blood pressure, lowers the stress on the heart, and reduces fluid build-up in the lungs. It is often used in conjunction with Furosemide® or Digoxin®.
It is best to give this drug on an empty stomach. If stopping use of this drug, consult your veterinarian for an effective gradual reduction in dosage.
How It Works
Benazepril inhibits the angiotensin converting enzyme (ACE), an enzyme that converts angiotensin I to angiotensin II. Angiotensin II acts as a potent vasoconstrictor, meaning it narrows the blood vessels. By inhibiting this enzyme, it prevents the angiotensin II from ever being created and relaxes the blood vessels. This lowers the blood pressure and reduces the amount of work the heart has to do.
Store in a tightly sealed container at room temperature. Refrigerate the oral liquid.
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.
Side Effects and Drug Reactions
Benazepril may result in these side effects:
- Allergic reaction (labored breathing, hives, etc)
- Low blood pressure
- Changes in water intake and urination frequency
Benazepril may react with these drugs:
- Rimadyl (and other NSAIDs)
- Potassium supplements
DO NOT GIVE BENAZEPRIL TO PREGNANT OR LACTATING PETS
USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH LIVER DISEASE, KIDNEY DISEASE, OR BLOOD DISORDERS