PetMD Editorial
By PetMD Editorial on Nov. 7, 2012

Drug Info

  • Common Name: Naprosyn®, Aleve®
  • Drug Type: Non-steroidal anti-inflammatory drug (NSAID)
  • Used For: Inflammation, pain
  • Species: Dogs, Cats
  • Administered: Tablet
  • How Dispensed: Over the counter
  • FDA Approved: Yes

General Description

Naproxen is a Non-Steroidal Anti-Inflammatory drug (NSAID) which may be used for the treatment of inflammation in pets. It is typically prescribed to treat inflammation and fever. It is generally not recommended for use in dogs and cats due to the high risk of toxicity and overdose. Other NSAIDs may be used due to their low risk of side effects.

How It Works

NSAIDs work by reducing the enzyme COX-2. COX-2 is involved in the formation of prostaglandins which cause swelling and inflammation. Reduction of these factors reduce the pain and inflammation your pet experiences.

Storage Information

Store in a tightly sealed container. Read the storage instructions on the drug label as some forms may need to be refrigerated.

Missed Dose?

If you do miss a dose, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Naproxen may result in these side effects:

  • Loss of Appetite
  • Black, tarry stools
  • Vomiting
  • Abdominal pain
  • Dehydration
  • Diarrhea
  • Liver damage
  • Kidney damage
  • Ulceration of the digestive tract


Naproxen may react with these drugs:

  • Aluminum Hydroxide
  • Furosemide
  • Methotrexate
  • Warfarin Sodium
  • Corticosteroids
  • Other NSAIDs
  • Other drugs that may cause ulceration of the digestive tract

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH KIDNEY DISEASE, LIVER DISEASE, BLOOD DISORDERS OR HEART FAILURE

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PREGNANT PETS


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