Kaopectate® for Dogs and Cats: Uses and Side Effects
Kaopectate® is an over-the-counter human anti-diarrheal medication that veterinarians may recommend for dogs and cats in specific circumstances.
Because its active ingredient, bismuth subsalicylate, breaks down into a substance related to aspirin, Kaopectate® should only be given to pets under a veterinarian’s direction.
Here’s what to know about how Kaopectate® works, possible side effects, overdose risks, and safe use in dogs and cats.
Key Takeaways
- Kaopectate® is a human anti-diarrheal medication that should only be given to dogs or cats under veterinary supervision.
- Its active ingredient, bismuth subsalicylate, helps protect the gastrointestinal tract and reduce inflammation.
- Cats are particularly sensitive to medications containing aspirin-related ingredients, so Kaopectate® should not be given to cats without strict veterinary supervision.
- Side effects can include constipation and dark discoloration of the stool or tongue.
- A Kaopectate® overdose can be life-threatening and requires immediate veterinary attention.
What Is Kaopectate®?
Kaopectate® is an over-the-counter (OTC) anti-diarrheal medication for humans that may be used in dogs and cats in specific circumstances, but only under the direction and supervision of a veterinarian.
The active ingredient in Kaopectate® is bismuth subsalicylate, which is not FDA-approved for use in animals. Veterinarians may sometimes recommend it for dogs, cats, horses, cattle, swine, and ferrets.
There are many possible causes of diarrhea in dogs and cats, and treatment depends on the underlying cause. If your pet has diarrhea, speak with your veterinarian before giving any medication to determine the safest and most appropriate treatment.
Never give your pet a human medication without first speaking with your veterinarian.
FDA approval: Bismuth subsalicylate is the active ingredient in Kaopectate®, Pepto-Bismol®, Bismatrol, and Pink Bismuth. These human formulations are not FDA-approved as veterinary medications.
However, veterinarians may legally prescribe certain human medications, including Kaopectate®, for animals in specific circumstances. This is called extra-label or off-label use because the veterinary use is not described on the drug label.
How Kaopectate® Works
Kaopectate® works by helping protect the stomach lining and reducing inflammation caused by toxins and harmful bacteria in the gastrointestinal tract.
The active ingredient in Kaopectate®, bismuth subsalicylate, separates into two components in the body: salicylate and bismuth.
- Salicylate, the active ingredient in aspirin, helps reduce discomfort and inflammation in the gastrointestinal tract.
- Bismuth provides antibacterial properties.
Because bismuth subsalicylate breaks down into salicylate, there are potential harmful effects associated with aspirin in dogs and cats.
How To Give Kaopectate®
Give Kaopectate® only under the direction of your veterinarian and follow their instructions for proper use.
Because Kaopectate® is a human medication, your veterinarian will determine how it should be given to your pet.
Missed a Dose?
If you miss a dose of Kaopectate®, contact your veterinarian for guidance. Generally, they may instruct you to give it when you remember.
If it is almost time for the next dose, they may recommend skipping the missed dose and resuming the normal dosing schedule.
Do not give extra or double doses.
Kaopectate® Side Effects
Kaopectate® can cause side effects in dogs and cats, and more serious reactions may occur because the medication contains bismuth subsalicylate.
Possible side effects include:
- Constipation
- Gray-black or green-black discoloration of the stool and tongue
Important for cats: Kaopectate® should not be given to cats without strict veterinary supervision because cats are sensitive to products containing aspirin. Aspirin can be toxic in cats.
Kaopectate® breaks down into aspirin in the body. Pets that are sensitive or allergic to aspirin, have certain medical conditions, or take medications that interact with aspirin may experience more severe side effects, including:
- Vomiting
- Bleeding
- Black, tarry stool
- Weakness
- Abdominal pain
- Seizures
Human Side Effects
Kaopectate® is also an over-the-counter medication for people, but human and veterinary doses may differ. Because of possible side effects, pets should not be given medication intended for human use without veterinary guidance.
When To Call Your Veterinarian
Contact your veterinarian if:
- Your pet develops severe side effects.
- Your pet's condition worsens or does not improve with treatment.
- You suspect your pet has received an overdose.
- You have additional questions or concerns about using Kaopectate®.
Kaopectate® Overdose
An overdose of Kaopectate® can be life-threatening and requires immediate veterinary attention.
Signs of an overdose may include:
- Diarrhea
- Lethargy
- Vomiting
- Wobbliness
- Weakness
- Panting
- Loss of appetite
- Abdominal pain
- Seizures
- Kidney problems
If you suspect your pet has received an overdose, contact your veterinarian immediately, seek emergency veterinary care, or contact an animal poison control center. Consultation fees may apply.
- Pet Poison Helpline: (855) 764-7661
- ASPCA Animal Poison Control: (888) 426-4435
How To Store Kaopectate®
Store Kaopectate® tablets and liquids according to the product label and at controlled temperatures between 68 F and 77 F (20 C–25 C).
Storage instructions:
- Keep the container tightly closed to protect the contents from moisture and light.
- Always confirm storage requirements by reading the product label.
- Keep out of reach of children and pets.
Kaopectate® for Dogs and Cats FAQs
What can I give my dog to treat diarrhea?
Do not give Kaopectate® or another over-the-counter medication to your dog unless directed by your veterinarian.
There are many possible causes of diarrhea, and treatment depends on the underlying cause.
Contact your veterinarian before giving your dog medication so they can recommend the safest and most appropriate treatment based on your dog's medical history and condition.
Can dogs take Kaopectate®?
Kaopectate® may be used in dogs in specific circumstances, but only under the direction and supervision of a veterinarian.
Kaopectate® contains bismuth subsalicylate, a human medication that is not FDA-approved for use in animals. Your veterinarian will determine whether it is appropriate for your dog.
Can cats take Kaopectate®?
Kaopectate® should not be given to cats without strict veterinary supervision.
Cats are sensitive to products containing aspirin, and aspirin can be toxic in cats. Your veterinarian will determine whether Kaopectate® is appropriate for your cat.
Does Kaopectate® contain aspirin?
Kaopectate® contains bismuth subsalicylate, which separates in the body into bismuth and salicylate. Salicylate is the active ingredient in aspirin.
No vet writer or qualified reviewer has received any compensation from the manufacturer of the medication as part of creating this article. All content contained in this article is sourced from public sources or the manufacturer.
