PetMD Editorial
Written by:
PetMD Editorial
Published: December 21, 2012

Drug Info

  • Common Name: Deramaxx
  • Generics: No generics are available
  • Drug Type: Non-steroidal anti-inflammatory drug (NSAID) in a class called coxib
  • Used For: Pain and Inflammation associated with osteoarthritis
  • Species: Dogs
  • Administered: Tablets
  • How Dispensed: Prescription Only
  • Available Forms: 12mg, 25mg, 75mg, & 100mg Tablets
  • FDA Approved: Yes, for dogs


Deracoxib (Deramaxx) are indicated for the control of pain and inflammation associated with osteoarthritis and postoperative pain and inflammation due to orthopedic surgery and dental surgery in dogs.

Do NOT use in cats.

Dosage and Administration

Deracoxib (Deramaxx) should be given according to your veterinarian’s instructions. Do not change the way you give Deracoxib without speaking with your veterinarian first. The recommended dose of Deracoxib is 0.45mg - 0.91 mg/lb/day as a single daily dose, as needed. Inaccurate dosing may result in adverse reactions. For long-term treatment, it is best to use the lowest effect dose to provide relief. Deracoxib is given by mouth, but is best given with food.

Missed Dose?

If a dose of Deracoxib (Deramaxx) is missed, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your dog two doses at once.

Possible Side Effects

Deracoxib (Deramaxx) like other NSAIDS may cause some side effects. The most common side effects of Deracoxib involve digestive issues such as vomiting and decrease appetite. Other possible side effects of Deracoxib include:

  • Change in bowel movements (diarrhea, or black, tarry or bloody stools)
  • Change in behavior (decreased or increased activity level, incoordination, seizure, or aggression)
  • Jaundice (yellowing of gums, skin or whites of eyes)
  • Increase water consumption or urination changes (frequency, color, or smell)
  • Seizure
  • Skin irritation (redness, scabs, or scratching)
  • Stomach pain
  • Stomach ulcers
  • Unexpected weight loss

It is important to stop the medication and immediately contact your veterinarian if you think your dog has any medical problems or side effects while taking Deracoxib.


Deracoxib (Deramaxx) is for use in dogs only.  Deracoxib should not be given to dogs that are hypersensitive to deracoxib or other NSAIDs. Deracoxib should not be given with any other NSAIDs, including: Carprofen (Rimadyl), Meloxicam (Metacam), Etodolac (Etogesic), Firocoxib (Previcox), Aspirin.

Not for use in humans. Keep this and all medications out of reach of children.


Deracoxib (Deramaxx) should be stored at room temperature between 59° and 86°F (15-30°C).

Drug Interactions

Deracoxib (Deramaxx) should not be given with other NSAIDs or corticosteroids (e.g., prednisone, cortisone, dexamethasone or tramcinolone).

Signs of Toxicity/Overdose

Overdose of Deracoxib may cause:

  • Loss of appetite
  • Vomiting
  • Diarrhea
  • Dark or tarry stool
  • Increased thirst
  • Increase urination
  • Incoordination
  • Pale gums
  • Jaundice
  • Lethargy
  • Fast or heavy breathing
  • Behavior changes
  • Seizures              

If you suspect or know your dog has had an overdose, it could be fatal so please contact your veterinarian, an emergency vet clinic, or the Pet Poison Helpline at (855) 213-6680 immediately.

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