PetMD Editorial
By PetMD Editorial
Published: November 7, 2012

Drug Info

  • Common Name: Various common names
  • Drug Type: Antacids
  • Used For: Acid reflux, Peptic ulcers, Kidney failure, Heartburn
  • Species: Dogs, Cats
  • Administered: Oral liquids, capsules
  • FDA Approved: No

General Description

Antacids are used to reduce the acidity in the digestive tract by increasing the pH to a more basic level. It is used to treat symptoms associated with heartburn, acid reflux, and peptic ulcers. Some antacids may be effective in pets with kidney failure to reduce the amount of phosphate in the blood.


How It Works

Acidity in your pet’s digestive tract increases when acetylcholine, histamine, and gastrin stimulate cells in the stomach wall to release hydrochloric acid. Antacids neutralize the acid molecules, increasing the pH in your pet’s body and reducing the stomach irritation caused by the acid.

Storage Information

Store in a tightly sealed container at room temperature unless otherwise noted on the drug label.

Missed Dose

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Antacids may result in these side effects:

  • Loose stools with magnesium compounds
  • Constipation with aluminum or calcium compounds
  • Lack of appetite

Antacids may react with these drugs:

  • Tetracyclines
  • Chlordiazepoxide
  • Captopril
  • Chloroquine
  • Cimetidine
  • Corticosteroids
  • Digoxin
  • Ketoconazole
  • Nitrofurantoin
  • Penicillamine
  • Phenothiazines
  • Phenytoin
  • Ranitidine
  • Valproic acid
  • Aspirin
  • Quinidine
  • Ephedrine


USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH KIDNEY DISEASE - Long term use of aluminum or calcium compounds can cause damge to the kidneys. Antacids containing magnesium should not be used in pets with kidney failure.

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