By PetMD Editorial on Nov. 7, 2012

Drug Info

  • Common Name: Pepcid®
  • Drug Type: H2 blocker
  • Used For: Stomach ulcers
  • Species: Dogs, Cats
  • Administered: Tablets, Oral liquid
  • How Dispensed: Over the counter
  • Available Forms: 10 mg, 20 mg and 40 mg tablets
  • FDA Approved: No

General Description

Famotidine is a histamine (H2) blocker that is used to prevent and treat stomach and intestinal ulcers. It is often prescribed in the cases of parvovirus, irritable bowel syndrome, megaesophagous, and acid reflux to soothe inflammation and assist in healing. It is also used in the prevention of intestinal ulcers in pets with kidney failure.

Give this medication without food, as food will decrease its effectiveness.

How It Works

Histamine is a key component in the allergic reaction, causing inflammation and swelling. It can often cause stomach cramping and diarrhea as well. By inhibiting the H2 receptor, a receptor for histamine, Famotidine reduces the output of stomach acid. This reduces the pH of the digestive system, giving the ulcer in the stomach time and a more favorable environment to rest and heal.

Storage Information

Store in a tight container at room temperature protected from light and heat.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Famotidine may react with these drugs:

  • Digoxin
  • Ketoconazole
  • Antacids
  • Metoclopramide
  • Sucralfate

It is best to give these medications at least two hours prior or following the use of Famotidine.

Famotidine may also react with Azathioprine and other bone marrow suppressing drugs. Please consult your veterinarian before giving these or any other drug or herbal supplement to your pet while on Famotidine.

DO NOT GIVE FAMOTIDINE TO LACTATING PETS

USE CAUTION WHEN ADMINISTERING THIS DRUG TO OLDER PETS, PREGNANT PETS, OR PETS WITH KIDNEY DISEASE, LIVER DISEASE, OR HEART RHYTHM ABNORMALITIES


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