Salmonella Infection in Cats

3 min read

Salmonellosis in Cats


Salmonellosis is an infection found in cats caused by the Salmonella bacteria. Along with causing gastroenteritis and septicemia in cats, salmonellosis is a zoonotic bacterial disease, meaning it can be transmitted to humans.


Salmonellosis can also affect dogs. If you would like to learn more about how this disease affects dogs, please visit this page in the PetMD health library.


Symptoms and Types


The severity of the disease will often determine the signs and symptoms that are overtly present in the cats. Symptoms commonly seen in cats with salmonellosis include:


  • Fever
  • Shock
  • Lethargy
  • Diarrhea
  • Vomiting
  • Anorexia
  • Weight loss
  • Dehydration
  • Skin disease
  • Mucus in stool
  • Abnormally fast heart rate
  • Swollen lymph nodes
  • Abnormal vaginal discharge


Chronic forms of salmonellosis may exhibit some of these same symptoms; however, they will be more severe. These include symptoms:


  • Fever
  • Weight loss
  • Loss of blood
  • Non-intestinal infections
  • Diarrhea that comes and goes with no logical explanation, which may last up to three or four weeks, or longer




There are more than 2,000 different types of Salmonella, a Gram-negative enterobacteria. Typically, a host animal carrying the disease will have two or more different microorganisms or types of Salmonellae bacteria that cause this disease.


Risk factors include the cat's age, with younger and older animals most at risk due to their underdeveloped and/or compromised immune systems. Similarly, cats with weak immune systems or immature gastrointestinal tracts are at risk.


Cats receiving antibiotic therapy are also at risk because the healthy bacteria that line the digestive tract (or florae), may become imbalanced, increasing the risk of salmonellosis.




To confirm a diagnosis of salmonellosis, your veterinarian will examine your cat for different physical and pathological findings. Some cats infected with the bacteria do not show any clinical symptoms; others display gastroenteritis, a disease affecting the gastrointestinal system.



Other diagnostic features include:


  • Acute vomiting and diarrhea
  • Low albumin
  • Low platelet levels
  • Nonregenerative anemia
  • Abnormally low white blood cell count
  • Electrolyte imbalances, which may include sodium and potassium imbalances


Your veterinarian may want to also rule out other conditions that can result in similar symptoms, including parasites, dietary-induced stress (including allergy or food intolerances), drug or toxin-induced stresses, and diseases like viral gastroenteritis or bacterial gastroenteritis caused by E. Coli or other common bacteria.


Diagnostic procedures typically involve collecting urine and fecal samples for laboratory analysis. Your veterinarian may also find it helpful to conduct blood cultures.


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