Enlargement of Esophagus in Cats

Alex German
Apr 11, 2010
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Megaesophagus in Cats


Megaesophagus is the enlargement of the esophagus, a muscular tube that runs from the throat to the stomach. The esophagus functions solely to deliver food from the mouth to the stomach.  Magaesophagus involves a lack of motility required for the movement of food and liquid down to the stomach and can be the result of a variety of underlying diseases or causes.


Siamese and Siamese-related cats are found to be predisposed to the this condition.


Symptoms and Types





Megaesophagus can either be congenital in nature (born with) or acquired later in life. The congenital form is typically idiopathic or due an unknown cause; although it is rarely due to myasthenia gravis. The acquired form is also commonly idiopathic, but may also be due to:


  • Neuromuscular disease (e.g., myasthenia gravis, dysautonomia, myositis)
  • Esophageal tumor
  • Foreign body in esophagus
  • Inflammation of esophagus
  • Toxicity (e.g., lead, thallium)
  • Parasitic infections




Your veterinarian will first ask you for a thorough history of your cat’s health. He or she will then perform a complete physical examination on your cat and attempt to differentiate, with your description, whether it is regurgitating or vomiting, which is important in ruling out underlying diseases that cause vomiting. The shape of expelled material, presence of undigested food, and length of time from ingestion to vomiting (or regurgitation) will also help differentiate between these two issues.


Routine laboratory tests, including complete blood count (CBC), biochemistry profile, and urinalysis results, are usually normal in cats with megaesophagus. However, abnormalities related to underlying diseases or complications, like aspiration pneumonia, may be seen. Radiographic studies will show the enlarged esophagus filled with fluid, air, or food, and will help identify abnormalities related to aspiration pneumonia.


More advanced techniques, like esophagoscopy, will be sometimes be employed, too. Esophagoscopy allows for the examination of the interior of the esophagus using an esophagoscope, a thin, tube-like instrument with and light and lens for viewing the inner areas of esophagus. It also allows for the removal of foreign bodies, evaluation of obstruction, and neoplasia.

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