Phenoxybenzamine

PetMD Editorial
Written by:
PetMD Editorial
Published: November 7, 2012

Drug Info

  • Common Name: Dibenzaline®
  • Drug Type: Alpha blocker
  • Used For: Bladder problems, Tumor associated high blood pressure
  • Species: Dogs, Cats
  • Available Forms: 10mg capsules
  • FDA Approved: No

General Description

Phenoxybenzamine is a smooth muscle relaxer used in pets reduce bladder problems. It is often used in dogs or cats that had a recent urinary blockage. It may also be used to treat other disorders such as high blood pressure.

How It Works

Alpha adrenoreceptors are located in the blood vessel walls, and the blockage of them leads to the opening of the vessels, lowering blood pressure. Phenoxybenzamine also relaxes the urethral sphincter muscles, which can relax the urethra, allowing urine to pass.

Storage Information

Store in a tightly sealed container at room temperature.

Missed Dose?

If you miss a dose, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Phenoxybenzamine may result in these side effects:

  • High blood pressure
  • Low blood pressure
  • Increase pressure in the eye
  • Lethargy
  • Vomiting
  • Nasal congestion
  • Diarrhea
  • Loss of appetite


Phenoxybenzamine may react with these drugs:

  • Alpha agonists
  • Beta agonists
  • Sypathomimetic

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH KIDNEY DISEASE, HEART DISEASE, OR CONGESTIVE HEART FAILURE


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