- Drug Name: Enalapril
- Common Name: Enacard®, Vasotec®
- Drug Type: ACE Inhibitor
- Used For: Heart failure
- Species: Dogs, Cats
- How Dispensed: Prescription only
- Available Forms: 1 mg, 2.5 mg, 5 mg, 10 mg and 20 mg tablets, oral liquid
- FDA Approved: Yes, for dogs
Enalapril is used to treat minor to severe heart failure, dilated cardiomyopathy, or high blood pressure. It may also be used to treat chronic kidney failure. It lowers blood pressure, lowers the stress on the heart, and reduces fluid build-up in the lungs. It is often used in conjunction with Furosemide® or Digoxin®.
How It Works
Enalapril inhibits the angiotensin converting enzyme (ACE), an enzyme that converts angiotensin I to angiotensin II. Angiotensin II acts as a potent vasoconstrictor, meaning it narrows the blood vessels. By inhibiting this enzyme, it prevents the angiotensin II from ever being created and relaxes the blood vessels. This lowers the blood pressure and reduces the amount of work the heart has to do.
Store in a tightly sealed container at room temperature. Refrigerate the oral liquid.
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.
Side Effects and Drug Reactions
Enalapril may result in these side effects:
- Allergic reaction (labored breathing, hives, etc)
- High blood pressure
- Ulceration of the digestive tract
Enalapril may react with these drugs:
- Rimadyl (and other NSAIDs)
- Potassium supplements
- Drugs that may cause ulceration of the digestive tract
DO NOT GIVE ENALAPRIL TO PREGNANT OR LACTATING PETS
USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH LIVER OR KIDNEY DISEASE