Amlodipine Besylate

PetMD Editorial
By PetMD Editorial
Published: July 18, 2014

Drug Info

  • Common Name: Norvasc
  • Generics: Yes
  • Drug Type: Calcium Channel Blocker
  • Used For: Hypertension
  • Species: Dogs, Cats
  • Administered: Oral
  • How Dispensed: Prescription Only
  • Available Forms: 2.5mg, 5mg
  • FDA Approved: Yes


Amlodipine Besylate is used to treat hypertension (high blood pressure), especially in cats with kidney disease.

Dosage and Administration

Amlodipine Besylate should be given according to your veterinarian’s instructions. 

Missed Dose?

It is important doses are not missed, as a missed dose can result in a sudden rise in blood pressure which could lead to blindness, kidney damage, seizures or collapse. If a dose of Amlodipine Besylate is missed, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not give two doses at one time.

Possible Side Effects

Side effects from Amlodipine Besylate could include but are not limited to:

  • Drowsiness
  • Loss of appetite
  • Weight loss
  • Rapid heart rate
  • Swelling of the gums

Please contact your veterinarian immediately if you notice any side effects.


Do not use in animals that are allergic to Amlodipine Besylate or in breeding, pregnant or lactating females and breeding males. Use with caution in animals with heart failure or liver disease and do not miss any doses, as a missed dose could result in a sudden rise in blood pressure, which can cause adverse reactions.


Amlodipine Besylate should be stored between 68-77oF (20-25°C). Do not store in direct sunlight or within a child’s reach.

Drug Interactions

When using Amlodipine Besylate, please consult your veterinarian about any other medications you are currently giving your pet, including supplements, as interaction could occur.  When using with aspirin, diuretics (e.g., Furosemide/Salix), certain beta-blocker heart medications (e.g., Propanolol or Atenolol) or other medications that lower blood pressure, please be sure to consult with your veterinarian as interactions may occur.

Signs of Toxicity/Overdose

Overdose of Amlodipine Besylate may cause:

  • Dizziness or staggering
  • Slow heart rate
  • Collapse

If you suspect or know you pet has had an overdose, please contact your veterinarian, an emergency vet clinic or the Pet Poison Helpline at (855) 213-6680 immediately.

Help us make PetMD better

Was this article helpful?

Get Instant Vet Help Via Chat or Video. Connect with a Vet. Chewy Health

Subscribe to PetMD's Newsletter

Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox.