PetMD Seal

Bacterial Infection (Tyzzer Disease) in Dogs

1 min read

Tyzzer Disease in Dogs


Tyzzer disease is a bacterial infection caused by the bacterium Clostridium pilformis. The bacterium is thought to multiply in the intestines and once reaching the liver, causing severe damage. Young dogs are at high risk of developing the disease.


Symptoms and Types


Due to the severity of the liver damage, some dogs with Tyzzer disease may die within 24-48 hours. Some early signs of the disease include:


  • Lethargy
  • Depression
  • Loss of appetite
  • Diarrhea
  • Abdominal pain and discomfort
  • Liver enlargement
  • Abdominal distension
  • Low body temperature




The bacterium Clostridium piliformis.




Your veterinarian will conduct a complete medical history and perform a physical examination on your dog. He or she will then use routine laboratory tests including complete blood count, biochemistry profile, electrolyte panel, and urinalysis to assess the condition of your dog and severity of the disease.


If your dog has Tyzzer disease, the biochemistry profile testing may reveal abnormally high levels of liver enzymes, especially shortly before the dog's condition becomes dire.



Related Articles

Bacterial Infection (Tularemia) in Dogs

Tularemia is a zoonotic bacterial disease that is occasionally seen in dogs. It is associated with multiple animal species, including humans,...

Racoon Disease in Dogs

Most commonly called “raccoon disease” because of its prevalence in the raccoon population, baylisascariasis comes from contact with raccoon...

Rocky Mountain Spotted Fever in Dogs

Rocky Mountain spotted fever is one of the most commonly known tick-borne diseases to affect dogs and humans. It belongs to a class of diseases...

Mumps in Dogs

The parotid salivary gland is located just underneath each ear in the dog. When a dog is exposed to a person who is infected with a viral infection...