Bartonellosis is an emerging infectious bacterial disease in dogs, caused by the gram-negative bacteria Bartonella, which may affect cats and humans as well. In humans, infection of the Bartonella bacterium is also known as cat scratch disease (CSD), though it may not have necessarily been acquired through a cat's scratch or bite.
The Bartonella spp bacterium is transmitted to dogs via fleas, sand flies, lice, and ticks. Herding and hunting dogs are at higher risk due to increased exposure to vectors like sand flies, lice, fleas, and ticks. Another important aspect of this disease is that both dogs and humans share a common spectrum of clinical symptoms.
This is a zoonotic disease, meaning that it can be transmitted between animals and humans. Fortunately, this disease is not fatal for humans, but it still poses great risks to immunocompromised patients, such as those with the AIDS virus, or those undergoing chemical treatment.
Symptoms and Types
The majority of human patients are less than 21 years of age. The following symptoms are commonly seen in humans:
- Red papule (small sized solid bump) at bite or scratched site
- Painful lymph nodes of involved area
- Shivering and chills
- Lack of appetite
- Pain in muscles
- Altered brain functions
- Inflammation of conjunctiva of eye (pink eye)
Symptoms in dogs include:
- Enlargement of spleen and liver
- Swelling and inflammation of lymph nodes
- Inflammation of heart’s muscles
- Inflammation and irritation of nose
- Inflammation of eye
- Nasal discharge and /or nose bleed
- Inflammation of brain
- Many other symptoms similar to that in humans
- Bacterium Bartonella infection
- History of flea or tick infestation
- Transmission in dogs is through sand flies, lice, ticks and flea exposure
- Dogs living in rural environments are at increased risk
- Transmission of the disease from dogs to humans is suspected to be through bites
There is usually a history of dog bite in affected humans. Symptoms of infection of the Bartonella bacterium include a characteristic papule at the site of the bite wound.
If your dog is suspected of being infected with Bartonella spp., your veterinarian will conduct a complete examination, which will include laboratory ordered blood tests, a biochemistry profile, and a urinalysis.
Various abnormalities may be present, such as a decreased number of platelets (the cells required for blood clotting), or anemia. An increased number of white blood cells (WBCs), or leukocytosis may also be evident in blood testing. Biochemistry profiling may reveal abnormal liver enzymes and a decreased concentration of albumin (a protein in blood) in affected dogs. Confirmation of the presence of Bartonella spp. will also involve a positive result from growing, or culturing the organisms from a sample of infected blood. A polymerase chain reaction (PCR) test is a more advanced method for detecting bacterial DNA using a sample of tissue taken from lesion.
A lesion of the skin less than half a centimeter in diameter
The prediction of a disease’s outcome in advance
An in-depth examination of the properties of urine; used to determine the presence or absence of illness
Small structures that filter out the lymph and store lymphocytes
A product made of fluid, cell waste, and cells
An increase in the number of white blood cells (abnormal)
A condition of the blood in which normal red blood cell counts or hemoglobin are lacking.
The singular form of the word bacteria; a tiny, microscopic organism only made up of one cell.
A change in the way that tissue is constructed; a sore
A type of protein that can be dissolved in water; found in milk, egg white, certain muscle, blood, and some urine.
Small, wingless insects that live as parasites on humans and some animals