Proin

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General Description

Proin® is given to pets that have trouble with urinary incontinence. This problem is most common in older spayed females, but often happens in males as well. Urinary incontinence is uncommon in cats, but may be treated with Proin® if found. In some cases of urinary incontinence, Proin® may be used in conjunction with an estrogen, Diethylstilbestrol.

How It Works

Phenylpropanolamine works releasing norepinephrine, which stimulate the alpha-adrenergic and beta-adrenergic receptors. One of the many organs these receptors effect are the sphincter mucles.  The sphincter muscles are those that surround the urethra (where urine flows from the bladder on out), allowing it to open or close. Proin® strengthens these muscles making the urethra tighter, preventing your pet from subconsciously urinating.

Proin® is typically given 2-3 times a day. It will take several days of taking this drug before results are seen.

Storage Information

Store in a tightly sealed container at room temperature.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Proin® may result in these side effects:

• Loss of appetite
• Restlessness
• Aggression
• Hypertension

Proin® may react with these drugs:

• Sympathomimetic drugs
• Amitraz
• Aspirin
• Tricyclic anti-depressants
• Rimadyl (or other NSAIDs)
• Anipryl
• Reserpine
• Ganglionic blocking agents
• Digoxin
• Monoamine oxidase inhibitors

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PREGNANT OR LACTATING PETS OR PETS  WITH DIABETES MELLITUS, ENLARGED PROSTATE GLANDS, HYPERTHYROIDISM, GLAUCOMA, HEART DISEASE OR HEART RHYTHM ABNORMALITIES