Hi stranger! Signing up for MypetMD is easy, free and puts the most relevant content at your fingertips.

Get Instant Access To

  • 24/7 alerts for pet-related recalls

  • Your own library of articles, blogs, and favorite pet names

  • Tools designed to keep your pets happy and healthy

or Connect with Facebook

By joining petMD, you agree to the Privacy Policy.


This product is available at  

Buy it now

Pet360.com is the most comprehensive online resource for pet parents.

Drug Details

  • Drug Name: Ketoconazole
  • Common Name: Nizoral®, Ketochlor®
  • Drug Type: Antifungal
  • Used For:
  • Species: Dogs, Cats
  • Available Forms: 200 mg tablets, shampoo
  • FDA Approved: No

General Description


Ketoconazole is an antifungal drug effective against fungus of the lymph nodes, skin, nails, respiratory system, bone, and other parts of your pet’s body. A shampoo that mixes Ketoconazole with Chlorhexidine is used to treat fungal and bacterial skin infections.


Other forms of this drug- Itraconazole and Fluconazole- have been produced to improve upon the number of side effects and effectiveness for certain types of infections. Some fungi have shown resistance to Ketoconazole, such as Candida albicans.


Giving Ketoconazole with food may assist with absorption and reduce stomach upset.


How It Works


Ketoconazole works by inhibiting production of the fungal cell wall. This causes the fungus to be structurally inadequate so that it leaks and dies. In smaller doses, in can be used to inhibit the reproduction of the fungus.


Storage Information


Store in a tightly sealed container at room temperature and protected from heat or light.


Missed Dose?


Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.


Side Effects and Drug Reactions


Ketoconazole may result in these side effects:

  • Inhibited synthesis of cortisone
  • Dizziness
  • Vomiting
  • Diarrhea
  • Loss of appetite
  • Bleeding of the mouth
  • Sensitivity to light


Ketoconazole also blocks the systhesis of cortisone in the adrenal gland, which in some cases may be a harmful side effect, but when used correctly, it’s an effective treatment against Cushing’s syndrome.


Ketoconazole may react with these drugs:

  • Aminophylline
  • Cisapride
  • Astemizole
  • Triazolam
  • Cyclosporine
  • Methylprednisolone
  • Mitotane
  • Phenytoin sodium
  • Rifampin
  • Theophylline
  • Warfarin sodium
  • H2 Blockers
  • Antacids






Discover More Medications