- Health Library
- PetMD U
Dexamethasone is many times more potent than other anti-inflammatory and immunosuppressing drugs including hydrocortisone and prednisone. It is often mixed with other drugs to treat difficult ear, eye, and skin infections. It reaches every system in the body and therefore is used to treat many disorders:
Dexamethasone is also used in some diagnostic tests, including the Low-Dose Dexamethasone Suppression test (LDDS). This test involves an initial baseline blood sample, an injection of the Dexamethasone, and two subsequent blood draws 4 and 8 hours later. Dexamethasone will suppress the amount of cortisol in a healthy dog, and the cortisol levels will be less than the level before the injection. In a Cushing’s syndrome dog, the levels will be elevated due to an excessive amount of cortisol being produced.
Dexamethasone is a corticosteroid known as a glucocorticoid. Corticosteroids are meant to resemble a naturally occurring hormone produced in the adrenal cortex, cortisol. Corticosteroids act on the immune system by blocking the production of substances that trigger inflammatory and immune responses.
Keep in a tightly sealed container at room temperature unless otherwise noted. Keep injection protected from light.
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.
Dexamethasone may result in these side effects:
Use caution and discuss with you veterinarian before administering Dexamethasone to animals with these conditions:
Dexamethasone may react with these drugs: