Although there is no definitive treatment for equine Cushing's disease, there are a handful of ways to manage and effectively control it. Pergolide is the medication of choice; anywhere from 0.2 to 5 milligrams orally per day has been shown to stabilize the health of most horses. If effective, the veterinarian may then gradually reduce the dosage.
Outside of pergolide, bromocriptine is another drug that has been used for managing Cushing’s disease in horses, though it is less popular than pergolide. Cyproheptadine is another drug that has been utilized for treating this condition as well. Before pergolide, cyproheptadine was the drug of choice for Cushing's, and in some cases a combination of cyproheptadine and pergolide is used to manage the condition.
After diagnosis and starting medication for Cushing’s disease, there are other management practices one can implement to help a horse with this condition. Horses with Cushing's disease are extremely prone to laminitis, a debilitating inflammatory condition inside the hoof. Regular farrier visits and limited access to lush pasture will help prevent this. Careful management of the horse's diet will help combat weight loss. Lastly, because Cushing's disease weakens the horse's immune system, make sure to properly clean and disinfect any superficial wounds found on the horse's body.
The gland that is found at the bottom of the brain whose job is to maintain appropriate levels of hormones in the blood
The long hair at the back of the neck on a horse
The hard outside of the feet of certain animals, like horses, cattle, goats, and pigs
The name for the species of horses, donkeys, mules
An inflammation of the lamina in horses; causes pain or congestion of the lining