Chordomas and Chondrosarcomas in Ferrets
A chordoma is a slow-growing tumor on a ferret's spine or tail which arises from remnants of notochords -- flexible, rod-shaped bodies that are located directly beneath the animal's nerve cord.
Chordomas do not metastasize (spread throughout the body), although they are locally invasive in the spinal cord. This compression of the spinal cord can cause ferrets to become paralyzed or show loss of some pain perception. Surgery can relieve the compressed spinal cord and usually return the ferret to normal.
Chondrosarcomas, meanwhile, are a type of metastatic (spreads throughout the body) cancer of the cartilage. Surgery is not usually helpful with this type of cancer, as the cancer spreads quickly throughout the ferret's body, and often before it is ever diagnosed.
The prognosis for chondrosarcoma is much worse than the prognosis for a chordoma.
Symptoms and Types
Chordoma and chondrosarcoma tumors may be found on a ferret's spine, neck, upper back and the tip of the tail. Chondrosarcoma tumors, in addition, may be found on the ferret's breastbone or ribs. Both types of tumors are most often smooth, hairless, slow-growing, and painless to the touch. Some tumors are hard.
Unfortunately, there is no known cause to these two tumorous conditions.
Your veterinarian will perform a complete physical exam on the ferret. He/she will take a thorough history from the owner, and order a blood chemical profile, a complete blood count, an electrolyte panel, and a urinalysis to see if the ferret is suffering from systemic signs of disease.
A biopsy of the ferret's nodule should be taken. Slides of the tissue (histopathology) can be tested using immunohistochemistry techniques for cytokeratin. If cytokeratin is present, the nodule is a chordoma and the prognosis is very good. However, if the test for cytokeratin is negative, the ferret has chondrosarcoma.
Magnetic resonance imaging (MRI) should be done when ferrets have chordoma, as this can show the extent of compression the spinal cord is undergoing and is more accurate than a myelogram.
A small lump or mass of tissue
The prediction of a disease’s outcome in advance
An in-depth examination of the properties of urine; used to determine the presence or absence of illness
A bundle of fibers that are used in the process of sending impulses through the body
Something that is related to the whole body and not just one particular part or organ
A picture that is taken of the spinal cord after dye is injected; may also be used to take a count of white blood cells
The process of removing tissue to examine it, usually for medical reasons.
An animal’s sternum
The process of removing all or part of a body part; usually refers to a limb (arm or leg) and is done for medical reasons.