Hi stranger! Signing up for MypetMD is easy, free and puts the most relevant content at your fingertips.

Get Instant Access To

  • 24/7 alerts for pet-related recalls

  • Your own library of articles, blogs, and favorite pet names

  • Tools designed to keep your pets happy and healthy

or Connect with Facebook

By joining petMD, you agree to the Privacy Policy.

Cushing's Disease in Dogs



Dogs with non-spreading adrenal tumors and small carcinomas will be surgically treated in most cases. Medical treatment to stabilize your pet before surgery may be necessary.


Many dogs can be treated with drugs; the type will be dependent on the location and type of tumor. These drugs can have serious side effects, so dogs taking them should be closely monitored.


Living and Management 


If your dog is being treated with medications for this condition, you will need to be prepared to continue treatment for the life of your pet. You will need to be observant of any adverse reactions to medications. Signs of an adverse reaction are lack of energy, weakness, lack of appetite, vomiting, diarrhea, and possible difficulty walking. If any of these side effects do occur, you should discontinue the medication, contact your veterinarian, and administer prednisone, which your veterinarian will have prescribed for you. If your dog does not respond to the prednisone, it should be taken immediately to the veterinarian for an emergency visit.


Your veterinarian will schedule a follow-up visit around eight days after initial treatment if your dog is receiving the oral medication mitotane for pituitary-dependent hyperadrenocorticism. If it is being treated for an adrenal tumor, you will need to take your dog for a follow-up visit around 10-14 days after initial treatment. Once your dog has stabilized, you will need to return to the veterinarian for follow-up appointments at one, three, and six months, and then every three to six months after the first six months of treatment.


Dog Care Questions
Answered By

Q. From whom should I get my puppy? The local shelter, my neighbor, a breeder, or a pet supply store?

A. Many people believe that it is better to get a puppy from a reliable breeder. While...

Read More
Q. How do I select a quality dog breeder?

A. To choose a quality breeder, take the time to conduct a thorough research on the...

Read More
Q. Should I get a mixed breed or purebred puppy?

A. A purebred puppy is a better option for some people because there is a better idea...

Read More
View All the Questions

Featured Breed


Old English Sheepdog

Featuring Piper
Also known as the Bobtail, the Old English Sheepdog is a dog breed developed in England in the early 19th century for the purpose of cattle herding. This shag-like dog may have an unusual...