Hi stranger! Signing up for MypetMD is easy, free and puts the most relevant content at your fingertips.

Get Instant Access To

  • 24/7 alerts for pet-related recalls

  • Your own library of articles, blogs, and favorite pet names

  • Tools designed to keep your pets happy and healthy



or Connect with Facebook

By joining petMD, you agree to the Privacy Policy.

PetMD Seal

Water Diabetes in Dogs

ADVERTISEMENT

Diabetes Insipidus in Dogs

 

Diabetes insipidus (DI) is a rare disorder that affects water metabolism, preventing the body from conserving water and releasing too much of it. This condition is characterized by increased urination, dilute urine (so-called insipid, or dull urine), and increased thirst and drinking. This disease is not related to diabetes mellitus (insulin diabetes).

 

Symptoms and Types

 

There are two main types of DI that affect dogs: neurogenic (or central diabetes insipidus) and nephrogenic diabetes insipidus. In neurogenic DI, the cause is due to a lack of the hormone vasopressin, which regulates the body's retention of water. The release of vasopressin is produced and regulated by the hypothalamus (in the brain), so a dysfunction in its release may be due to a head injury, or to a tumor in the brain. Vasopressin is produced in the hypothalamus into the connected pituitary gland, and is then released into the bloodstream. A lack of vasopressin may be due to a failure in the hypothalamus, or a failure in the pituitary gland. A significant number of cases is idiopathic.

 

Nephrogenic DI, meanwhile, can be caused by a deficiency of antidiuretic hormone (ADH), which functions to stimulate the capillary muscles and reduce the flow of urine, effectively conserving water for the body's various functions. The cause is found in the kidneys and their inability to respond appropriately to ADH, allowing too much water from the body to escape into the urine.

 

This is typically an acquired condition, and may be due to amyloidosis of the kidney, cysts on the kidney, or an imbalance of electrolytes.

 

Other common symptoms seen in dogs with DI include:

 

  • Increased urination (polyuria)
  • Increased drinking (polydipsia)
  • Decreased urination with dehydration
  • Housesoiling—occasional
  • Poor hair coat 

 

Causes

 

Inadequate secretion of antidiuretic hormone ADH

  • Congenital defect
  • Unknown causes
  • Trauma
  • Cancer

 

Renal insensitivity to ADH

  • Congenital
  • Secondary to drugs
  • Secondary to endocrine and metabolic disorders
  • Secondary to renal disease or infection

 

 

Diagnosis

 

Your veterinarian will perform a complete physical exam on your dog and ask you a series of questions to determine its state of health and the onset of symptoms. He or she will also order a blood chemical profile, a complete blood count, a urinalysis and an electrolyte panel.

 

Plasma ADH levels, for example, can be directly tested to differentiate between neurogenic, or central diabetes insipidus, and nephrogenic diabetes insipidus.

 

Magnetic resonance imaging (MRI) or computed tomography (CT), meanwhile, are useful for locating pituitary tumors and/or kidney disorders. A modified water deprivation test and/or an ADH supplementation trial can also be done to monitor body water loss.

 

 

Related Articles

Diabetes with Coma in Dogs
In the case of diabetes mellitus, the pancreas is not capable of making enough insulin....
READ MORE
Diabetes with Ketone Bodies in Dogs
Diabetes is a medical condition in which the body cannot absorb sufficient glucose,...
READ MORE
Liver Inflammation (Chronic) in Dogs
Hepatitis, a medical condition used to describe long-term, ongoing inflammation of...
READ MORE
  • Lifetime Credits:
  • Today's Credits:
Hurry Before All Seats are Taken!
Enroll
Be an A++ Pet Parent! Take fun & free courses to earn badges & certifications. Choose a course»
Search dog Articles

 

Latest In Dog Nutrition

The Role of Exercise in Pet Weight Loss
Exercise is beneficial for our pets in many ways, including weight loss, and here's...
READ MORE
5 Reasons Life Stage Diets Help Improve Pet ...
Balanced and complete nutrition is important for any animal. However, the nutritional...
READ MORE
How Obesity May Shorten Your Pet's Lifespan
Obesity is a nationwide epidemic for our pets. Unfortunately, being obese can shorten...
READ MORE
Around the Web
MORE FROM PETMD.COM