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Adenovirus 1 in Dogs

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If the infection is in the very early stage and is uncomplicated, treatment may be given on an outpatient basis. However, treatment is usually given inpatient. Fluid therapy will be given for electrolyte imbalances that result from vomiting and diarrhea. Potassium and magnesium are often very low and need to be supplement immediately. Blood component therapy will be given for coagulopathy (disorders in the blood's ability to clot). With overt DIC, fresh blood products and low molecular weight heparin will need to be sued to stabilize your dog's condition.


Nutritional support will include giving frequent small meals as tolerated, optimizing nitrogen intake, and feeding the dog according to protein needs. The amount of protein will depend entirely on your dog's individual condition, as some dogs will have high protein in the body and some will have low. Inappropriate protein restriction may impair tissue repair and regeneration. Nitrogen will be restricted if your dog is showing obvious signs of hepatic encephalopathy (a neuropsychiatric abnormality that causes inflammation of the brain and is related to liver failure).


Partial intravenous nutrition will be given for a maximum of five days, or preferably, total intravenous nutrition if oral feeding is not tolerated by the dog. Your doctor will prescribe antibiotics and/or fluid reducers as necessary.


Living and Management


The veterinarian will schedule follow up visits to monitor fluid, electrolyte, acid-base, and coagulation status, and to adjust supportive measures. Sudden kidney failure will also need to be monitored for. A highly digestible diet will need to be fed to your dog during recovery, and a safe place set aside to rest and recover from the illness. Restrict your dog's activity during the recovery period, as well as access to other pets. be especially mindful about cleaning up after your dog, as the virus can continue to be shed long after the recovery period.


Prevention of this infection requires a a modified live virus vaccination for this disease at six to eight weeks of age. The initial vaccination is followed by two booster shots given at three to four weeks apart until the dog reaches 16 weeks of age, with an additional booster given at one year. This is a highly effective vaccine. 



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