Q. Shetland Sheepdog on Revolution no adverse reaction. Turned 2 and suddenly he is disoriented and anxious for about 1 hour after applying.

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A. I would not recommend using Revolution on him in the future but to discuss other options for flea and heartworm prevention in your area. Shetlands can be sensitive to a wide range of drugs due to a genetic difference altering the way drugs are kept way/allowed through to their brain. It is possible there was a difference in the way his body absorbed the drug today (small wound/abrasion on the skin, he was warmer/wetter?)

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