- Drug Name: Amitriptyline
- Common Name: Elavil®
- Drug Type: Tricyclic antidepressant
- Used For: Behavioral problems
- Species: Dogs, Cats
- Administered: Tablets, Injectable
- How Dispensed: Prescription only
- FDA Approved: No
Amitriptyline is a tricyclic depressant used to treat many behavioral disorders in pets. It may be prescribed to treat separation anxiety, excessive grooming, death of a companion, or other problems. Amitriptyline has a pain relieving component, and is often used for anxiety disorders involving pain in cats.
How It Works
Serotonin and norepinephrine are chemicals in the brain that reverse the feelings of depression. They are released into the brain and then reabsorbed into the brain where they are no longer effective. Amitriptyline works preventing the reabsorption of these neurotransmitters back into nerve cells in the brain. This increases the levels of these chemicals and allows them to stick around the brain longer.
Store in a tightly sealed container at room temperature.
If you miss a dose, give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.
Side Effects and Drug Reactions
Amitriptyline may result in these side effects:
- Dry mouth
- Decrease in urination
- Dry eyes
- Increase in heart rate
- Increase in seizures in epileptic pets
Amitriptyline may react with these drugs:
- Antithyroid drugs
- Diazepam (and other central nervous system depressants)
- Monoamine Oxidase Inhibitors
- Protein bound drugs
- Selective serotonin reuptake inhibitors
USE CAUTION WHEN ADMINISTERING THIS DRUG TO PREGNANT OR LACTATING PETS, OR PETS WITH DIABETES MELLITUS, EPILEPSY, KIDNEY DISEASE, LIVER DISEASE, HEART DISEASE, OR HYPERTHYROIDISM