Propranolol

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General Description

Propranolol is a beta blocker that is used to control the heart rate of pets with irregular heart rhythms. It is also an effective blood pressure reducer. There is some discussion over it’s effectiveness in treating post-traumatic stress disorders and envenomation.

How It Works

Propranolol blocks the beta1 and beta2 receptors of epinephrine and norepinephrine. Epinephrine is commonly called adrenaline and is responsible for the elevated heart rate and "fight or flight" response when your pet is exposed to a stressor or fearful situation. By blocking the receptor for these hormones, the heart rate is decreased, the heart’s oxygen requirement is reduced, and the blood pressure is reduced, leaving you a calm pet with an unstressed heart.

Storage Information

Keep tablets in a tightly sealed container at room temperature.

Missed Dose?

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.

Side Effects and Drug Reactions

Propranolol may result in these side effects:

• Slowed heart rate
• Lethargy
• Low blood pressure
• Diarrhea
• Labored breathing

Propranolol may react with many drugs. Be sure to notify your veterinarian of your pet’s full medical history and all medications that they are currently taking. Propranolol may react with these drugs:

• Anesthesia
• Antacids
• Calcium channel blockers
• Negative Inotropes
• Phenothiazine
• Sympathomimetic
• Thyroid hormone
• Aminophylline
• Aspirin
• Chlorpromazine
• Cimetidine
• Digoxin
• Epinephrine
• Furosemide
• Hydralazine
• Insulin
• Lidocaine
• Methimazole
• Phenobarbital
• Phenytoin sodium
• Procainamide
• Quinidine
• Rifampin
• Succinylcholine chloride
• Terbutaline
• Theophylline

USE CAUTION WHEN ADMINISTERING THIS DRUG TO DIABETIC PETS

USE CAUTION WHEN ADMINISTERING THIS DRUG TO PETS WITH KIDNEY DISEASE, LIVER DISEASE, OR HEART FAILURE