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Adrenal disease is any disorder affecting the adrenal glands -- endocrine glands that are responsible for synthesizing certain hormones. It is a common and often systemic(Or far-reaching) disease affecting many animals; in this case, ferrets. Typically, adrenal disorders occur when a ferret produces too many hormones because of an underlying disease or condition.
Ferrets suffering from an adrenal disease display various signs and symptoms. These signs and symptoms are most common among ferrets that have been either neutered(Males) or spayed(Females). While ferrets typically begin to demonstrate symptoms between the ages of three and four, those as young as one or as old as seven years of age may also exhibit symptoms. Such symptoms, which vary in severity, may include:
Most ferrets develop this condition when the adrenal glands are damaged by the overproduction or underproduction of certain steroids from various causes, including stress and cancer tumors. Other causes may include adrenal tumors and hyperadrenocorticism, a condition characterized by the elevated concentration of the hormone cortisol. In ferrets, hyperadrenocorticism has been linked to the excessive use of sex steroids as a medical treatment.
To diagnose the ferret with adrenal disease, your veterinarian will first want to rule out other causes for the ferret’s symptoms, including lymphoma, urinary tract infections, cystitis, and alopecia. Otherwise, they will perform diagnostic tests to check if the ferret's blood sugar levels are low or if the steroid hormones estradiol and androstenedione are levels are abnormally high, both good indicators of adrenal disease. The veterinarian may also take X-rays of the animal to identify any cysts in its genital tracts or to detect an enlarged spleen or liver.
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