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Multiple Myeloma in Ferrets

Multiple myeloma is a rare form of cancer that is derived from a clonal population of cancerous (malignant) plasma cells. Although the cancerous cells typically concentrate in the bone marrow, they may also present themselves in the liver, spleen, kidney, pharynx, lung, gastrointestinal tract or lymph nodes. There have been only three reported cases of multiple myeloma disease in ferrets, but many others may go unreported.

Symptoms and Types

Symptoms depend on location and extent of disease. Some of the more common ones include:

• Weakness
• Lameness
• Pain at the site of the tumor
• Fractures
• Partial paralysis, or paralysis

Causes

Unknown

Diagnosis

There are many conditions and diseases that can cause these symptoms, so your veterinarian will want to rule out other potential causes. He or she will do a thorough physical exam, blood test, and urinalysis initially. Your veterinarian may then X-ray the ferret’s skeleton and perform an ultrasound to examine the visceral organs. He or she may also do a bone-marrow aspiration to determine the extent of plasma cells therein.