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Antibiotics such as tetracyclines or trimethoprim-sulfa are generally used to control the plague infection. However, since the bacterial disease can be transmitted from the infected prairie dogs to humans, it is generally advisable to euthanize any infected prairie dogs.
Isolate the infected prairie dog from other pets. Make sure that its living quarters are cleaned and sanitized. Be sure to wear gloves when cleaning the cage and disposing of contaminated materials, and wash your hands and arms thoroughly when done.
The risk of pet prairie dogs becoming infected and infecting their owners is very low; however, appropriate precautions should be taken with any newly wild-caught prairie dog.
In addition, prairie dogs should not be kept in outside cages in areas where plague is known to be a problem. Taking steps to provide appropriate sanitation and disinfection, wild rodent control, flea removal from all animal species present, isolation of sick prairie dogs and proper disposal of dead infected prairie dog is also useful in preventing transmission of plague disease to humans.
Small structures that filter out the lymph and store lymphocytes