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Non-inflammatory Myopathy of Endocrine Origin in Dogs

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This form of non-inflammatory myopathy is a type of muscle disease caused by endocrine maladies such as hypo- and hyperthyroidism. However, non-inflammatory myopathy of endocrine origin has also been associated with corticosteroid use.

Symptoms and Types

Muscle weakness
Loss of muscle bulk
Stiffness
Cramps
Regurgitation
Difficulty in swallowing (dysphagia)
Hoarseness (dysphonia)

Causes

Ultimately, this type of non-inflammatory myopathy is due to an endocrine disorder -- such as hyperadrenocorticism, hypothyroidism, or hyperthyroidism -- but may be immune-mediated or neoplastic in nature.

Diagnosis

You will need to give a thorough history of your dog’s health, including the onset and nature of the symptoms, to the veterinarian. He or she will then conduct a complete physical examination as well as a biochemistry profile, urinalysis, and complete blood count (CBC) to determine the type of endocrine disorder. Your veterinarian will also conduct thyroid and adrenal gland functions tests to confirm the diagnosis.

X-rays are conducted to evaluate pharyngeal and esophageal functions -- especially in patients with regurgitation and dysphagia -- while muscle samples are sent to veterinary pathologist for further evaluation.