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If a bone marrow transplant is conducted at an early age, the dog may be able to live a “near normal” life. However, this treatment is expensive, life-threatening, and not very helpful at a mature age. Also, a healthy donor is required for bone marrow transplant.
Enzyme replacement therapy is effective in dogs with mucopolysaccharidoses, but this, too, is an expensive recourse and has not been widely used in animals. Gene therapy, meanwhile, is thought to be an effective method of treatment, and is under evaluation for the treatment both in humans and animals.
Overall prognosis in dogs that have undergone bone marrow transplants is usually good. However, as the dog gets older, it will suffer from various problem, including eating difficulties. Therefore, they will require softer and easily palatable foods. Dogs with mucopolysaccharidoses are also prone to infections and may require antibiotic therapy.
Due to the genetic nature of this group of disorders, your veterinarian will recommend against breeding dogs with mucopolysaccharidoses.
The prediction of a disease’s outcome in advance
An in-depth examination of the properties of urine; used to determine the presence or absence of illness
Small structures that filter out the lymph and store lymphocytes
A substance that causes chemical change to another
a) Mass per volume b) The number of animals in a given area
Anything that looks different from what is considered to be normal and healthy for that species
The mating of animals who are closely related, like father and daughter or brother and sister