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Treatment

• Stop estrogen supplementation
• Supportive care, including antibiotics and blood transfusions
• Blood transfusions, if anemic
• Antibiotics in case of infections
• Masses may be examined via small scope instrument (laparoscopy)
• Masses may be removed via incision (laparotomy)
• If estrogen is not being administered artificially, surgical neutering in either male or female
• Removal of testicle or ovary may be considered for valuable breeding animals
• Testicular prosthetic devices are not advised
• Medications to increase blood production in bone marrow
• Medication to induce ovulation may be prescribed if there are cysts

Living and Management

Recovery may take a while -- up to several months -- so be prepared to provide long-term care for your pet. Be vigilant in providing prescribed medications and aware of any changes in your pet. Blood tests (and sometimes bone-marrow biopsies) must be performed to evaluate your pet's response to the therapy.

Do not give estrogen-containing compounds unless advised to by your veterinarian. Females will undergo tests to determine whether ovulation is occurring.

In addition, a male dog should not show signs of feminization once a testicular tumor has been removed.