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Overproduction of Estrogen in Dogs




  • Stop estrogen supplementation
  • Supportive care, including antibiotics and blood transfusions
  • Blood transfusions, if anemic
  • Antibiotics in case of infections
  • Masses may be examined via small scope instrument (laparoscopy)
  • Masses may be removed via incision (laparotomy)
  • If estrogen is not being administered artificially, surgical neutering in either male or female
  • Removal of testicle or ovary may be considered for valuable breeding animals
  • Testicular prosthetic devices are not advised
  • Medications to increase blood production in bone marrow
  • Medication to induce ovulation may be prescribed if there are cysts


Living and Management


Recovery may take a while -- up to several months -- so be prepared to provide long-term care for your pet. Be vigilant in providing prescribed medications and aware of any changes in your pet. Blood tests (and sometimes bone-marrow biopsies) must be performed to evaluate your pet's response to the therapy.


Do not give estrogen-containing compounds unless advised to by your veterinarian. Females will undergo tests to determine whether ovulation is occurring.


In addition, a male dog should not show signs of feminization once a testicular tumor has been removed.



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