Overproduction of Estrogen in DogsHyperestrogenism in Dogs
Estrogen -- a type of hormone -- is naturally produced in female dogs. It is responsible for normal sexual behavior and development, and the customary biological function of the female reproductive tract. Overproduction of estrogen can result in what is known as estrogen toxicity (hyperestrogenism). This can happen without any outside interference or it can occur when estrogens are being introduced artificially.
Estrogens sometimes cause abnormal (cystic) cells to line the uterus and this permits the invasion of bacteria from the vagina. The cervix is open during "heat," but if it is closed it can lead to a serious infection (pyometra). In addition, a concentration of estrogen can result in infertility, as well as an imbalance in the blood.
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