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Treatment

Once EPI has been diagnosed, treatment most commonly consists of supplementing your dog's diet with a pancreatic enzyme replacement. These enzyme supplements come in a powdered form which may be mixed with food. Also, if your dog is undernourished, vitamin supplements may be necessary.

Additional treatment depends on the root cause of EPI. Most causes of EPI, such as pancreatic acinar atrophy (see above), are irreversible. This means that life-long therapy and enzyme supplements will be needed.

Living and Management 

Avoid high-fat and high-fiber diets, which are more difficult for digestion. Weekly monitoring of your dog's  progress is necessary after initial treatment. Diarrhea should disappear within one week, and the consistency of stools should normalize soon after. Your dog will also begin to regain lost weight.

The dosage of enzyme supplements can be decreased as your dog's health and weight normalizes. Your veterinarian will guide you through this as your dog progresses.

Prevention 

Breed animals with pancreatic acinar atrophy is not advised, as the condition can passed along to offspring.