Apudoma in Dogs
Apudoma is a gastrointestinal tumor found in dogs and cats which secretes peptide hormones -- hormones that play a role in regulating metabolism, growth, development, and tissue function. In the long run, the tumor(s) can cause ulcers, damage the esophagus because of chronic reflux, and damage the lining of the intestines.
- Vomiting (sometimes with blood)
- Weight loss
- Loss of appetite (anorexia)
- Excessive thirst
- Tarry-looking stools
- Bloody stools (red blood)
- Abdominal pain
The cause of apudoma is currently not known.
Your veterinarian will want to rule out the following diseases:
- Kidney failure
- Inflammatory gastritis
- Stress-induced ulceration
- Ulceration brought on by medication (e.g., anti-inflammatory drugs or steroids)
- Uremia (condition which causes waste products to be retained in the blood)
- Other conditions associated with hyperacidity in the digestive tract and ulceration
The veterinarian will then run blood tests and chemistry analysis to identify if the animal has iron-deficiency anemia as a result of the gastrointestinal bleeding. Other concerns may include inadequate protein in the blood stream and an imbalance in electrolytes, due to the excessive vomiting.
In addition, an ultrasound of the abdomen can be used to determine whether there is a tumor in the animal's pancreas, as well as an aspirate of any masses to test for mast cell disease. An endoscopy and biopsy of the upper digestive tract may also be recommended.
Unfortunately, most of the apudoma tumors are cancerous (malignant) and by the time they’re discovered, it’s too late to treat them. However, aggressive medical management can sometimes relieve the symptoms and give the animal additional months (or even years) to live. Exploring a pancreatic mass surgically is important for diagnosis, but also to establish a treatment regimen.
Living and Management
Your pet will need frequent physical examinations, as well as careful observation at home. The veterinarian may also want to conduct X-rays and ultrasound exams from time to time to measure the progression of the disease and the effectiveness of the treatment. As there is no cure for the disease, the best you can hope for is to keep your pet comfortable and pain free for a few months, or even years.
Something that becomes worse or life threatening as it spreads
A compound made up of a group of amino acids; aids in the digestion of certain proteins
The digestive tract containing the stomach and intestine
A gland that aids in both digestive and insulin functions
The tube that extends from the mouth to the stomach
a) inhaling b) getting out fluid or gas by the act of sucking.
The process of removing tissue to examine it, usually for medical reasons.
The whole system involved in digestion from mouth to anus
A condition of the blood in which normal red blood cell counts or hemoglobin are lacking.
A medical condition in which the stomach becomes inflamed