Transfusion of fresh whole blood, fresh plasma, fresh frozen plasma, and cryoprecipitate will supply vWF to the blood. Component therapy (fresh frozen plasma or cryoprecipitate) is best for surgical prophylaxis (prevention) and nonanemic patients, to prevent red cell sensitization and volume overload. Patients with severe vWD may require repeated transfusion to control or prevent hemorrhage. If a dog lacking vWF requires surgery, a pre-operative transfusion should be given just before the procedure.
Living and Management
Most dogs with mild to moderate vWD will continue to have a good quality of life, requiring minimal or no special treatment. Dogs with more severe forms will require transfusion for surgery, and should be transfused if supportive care fails to control a spontaneous bleeding episode. Most of these dogs can be maintained comfortably, but their activities will need to be monitored and limited. If your dog has von Willebrand Disease and it has an episode of prolonged bleeding, call your veterinarian and take it to a veterinary clinic immediately for emergency treatment.
Prevention of something
To be allergic to or sensitive to a certain vaccine or medication
An in-depth examination of the properties of urine; used to determine the presence or absence of illness
A cell that aids in clotting
Extreme loss of blood
Any substance or item that the body of an animal would regard as strange or unwanted; a foreign disease or virus in the body (toxin, etc.)
A genetic condition in which blood does not properly coagulate
A condition of the blood in which normal red blood cell counts or hemoglobin are lacking.