
Treatment is usually non-specific unless the underlying cause is identified. Often, dogs suffering from myelodysplastic syndromes are prone to severe complications, such as infections, and require intensive nursing care. In these cases, these animal will undergo antibiotic therapy until their white blood cell count normalizes. These dogs are also more susceptible to severe anemia and hemorrhages and will require multiple blood transfusions.
Regular blood testing is required throughout treatment to evaluate the animal's progress. Unfortunately, the overall prognosis of these animals is not good, even after treatment. Maintaining the dog stable is, however, necessary to prevent further aggravation of symptoms.