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A transmissible venereal tumor, or TVT, is a naturally occurring tumor that is sexually transmitted from one dog to another. A high number of cases tend to be seen in large cities and temperate areas. TVT is usually seen in young, intact (non-neutered) dogs.
You may observe a red, tumorous mass bulging out of the surface membrane of the vagina, or on the penis. The tissue mass may break off upon manipulation. Blood drops may also be observed dripping from the vagina or penile foreskin. The dog will usually lick the affected area with frequency.
This condition is the result of direct contact with tumor cells from a diseased animal. It is transmitted through the act of sex, and can also be transmitted by oral contact. Intact, free roaming dogs are at greater risk of acquiring and spreading this disease.
Your attending veterinarian will need a complete health history, with as much information as possible regarding when the symptoms began, how much freedom your dog has to roam freely or whether there are other dogs that roam the area, if you have been attempting to breed your dog, etc.
The physical examination will focus especially on your dog's genital organs. A tissue sample of the mass will need to be taken for biopsy, and fluid samples will be taken for the standard laboratory tests, including the complete blood count, biochemistry profile and urinalysis. The results of these tests are usually within normal ranges, but in some cases blood cells or abnormal cancer cells may be found in the urine sample.
This type of tumor rarely spreads to other locations, but your doctor will need to visually confirm that it is not a malignant form of cancer. Visual diagnostics will include chest and abdominal X-rays to determine if there has been metastasis, and what stage it is in, if cancer is present. Your veterinarian will also palpate the lymph nodes of the affected area to determine how much the lymph nodes are reacting to the abnormality, an important distinguishing factor when cancerous cells are present.
A sample of lymph fluid will be sent to laboratory for further evaluation, to determine if cancerous cells are in the sample. The presence of cancerous cells in the lymph nodes is often a strong indication that the tumor is not benign. Treatment will be based on the results of these tests.
In some patients, the tumor may regress spontaneously without any treatment. Or your veterinarian may need to surgically excise the mass and begin medical therapy after surgery. If the tumor is benign, that is, not cancerous, a favorable prognosis that allows for a complete cure is generally expected. Your dog's overall well-being will be the deciding factor in how well treatment goes.
The overall prognosis following medical treatment is often excellent in affected patients. The risks are much higher, however, if the tumor is found to be malignant, Anticancer therapy presents many side-effects, especially if used on a long-term basis.
For example, the types of drugs that are used to suppress the growth of the cancerous cells can affect normal cells as well, lessening the protective effects of the immune system and resulting in your dog being at an increased risk of infections, sometimes serious. You will need to maintain a good plan of nutrition to help your dog to recover quickly without complications.
Your veterinarian will set up a follow-up treatment plan for subsequent treatment and routine checkups. The results of the laboratory tests, your dog's response to treatment, and any untoward side-effects related to therapy will guide changes to the treatment plan.
The growth of pathogens away from the original site of the disease
The prediction of a disease’s outcome in advance
An in-depth examination of the properties of urine; used to determine the presence or absence of illness
Something that becomes worse or life threatening as it spreads
Denotes an animal that is still able to reproduce or is free of cuts and scrapes
The process of removing tissue to examine it, usually for medical reasons.
To remove by surgical methods
Not being able to cause harm; the opposite of malignant.
Small structures that filter out the lymph and store lymphocytes