Nerve/Muscle Disorder in Cats
Myasthenia Gravis in Cats
A disorder of signal transmission between the nerves and muscles (known as neuromuscular transmission), and characterized by muscular weakness and excessive fatigue, is clinically known as myasthenia gravis. The disorder is congenital (present at birth) and familial (runs in families or lines).
It can also be acquired (not inherited, but present later in life/after birth), but as with other autoimmune diseases, it requires the appropriate genetic background for the disease to occur. Multiple factors are involved, including environmental, infectious, and hormonal influences. Acquired forms are known to affect Abyssinian and Somali breeds.
The congenital form becomes apparent at 6-8 weeks of age. The acquired form has a bimodal age of onset. Either at 1-4 years of age, or 9-13 years of age. There may be a slight susceptibility for females in the young age group, but none in the old age group.
Symptoms and Types
The acquired form may have several clinical presentations, ranging from localized involvement of the esophagus' muscles, the muscles of the throat, the muscles adjacent to the eye, and acute generalized collapse.
Any cat with acquired enlargement of the esophagus, loss of normal reflexes, or a mass in the front central area of the chest should be evaluated for myasthenia gravis. Regurgitation is common, but it is important to first differentiate it from vomiting.
Subtle nervous system findings
There are other disorders of neuromuscular transmission, such as tick paralysis, that may have the same symptoms, so your veterinarian will want to rule them out before coming to a conclusion about the diagnosis. To do that, he will need a careful history, thorough physical and neurologic examinations, and specialized laboratory testing.
A complete blood profile will be conducted, including a chemical blood profile, a complete blood count, and a urinalysis. Your veterinarian may also check for such things as thyroid functioning. Diagnostic imaging will include chest X-rays to look for an enlarged esophagus and aspiration pneumonia, and an ultrasound-guided exploration of the chest, to look for a mass. If a mass is found, a biopsy will need to be performed to confirm whether the growth is cancerous.
The return of food into the oral cavity after it has been swallowed
A gland found near the midline of the chest cavity; found mostly in young animals
An in-depth examination of the properties of urine; used to determine the presence or absence of illness
The area found between the muscles and the endings of the nerves
The term for weakness of the muscles
The process of removing tissue to examine it, usually for medical reasons.
The tube that extends from the mouth to the stomach
Term used to imply that a situation or condition is more severe than usual; also used to refer to a disease having run a short course or come on suddenly.
Narcolepsy and Cataplexy in Cats
Narcolepsy and cataplexy, disorders that affect the way an animal is able to physically...
Brain Tissue Undervelopment in Cats
Cerebellar hypoplasia occurs when parts of the cerebellum - a large portion of the...