Hi stranger! Signing up for MypetMD is easy, free and puts the most relevant content at your fingertips.

Get Instant Access To

  • 24/7 alerts for pet-related recalls

  • Your own library of articles, blogs, and favorite pet names

  • Tools designed to keep your pets happy and healthy

or Connect with Facebook

By joining petMD, you agree to the Privacy Policy.

PetMD Seal

Cushing's Disease in Cats



Treatment options are limited. Medical therapy has not been shown to be very effective, but surgical removal of the affected adrenal gland, or both affected glands, is usually recommended. The surgery will require hospitalization.


Living and Management


Medication is generally necessary for the remainder of the cat’s life to compensate for the removal of the adrenal glands. Your veterinarian will give explicit instructions for administering these medications, and those instructions should be carefully followed. Cats generally do not tolerate the medications very well, so working out the dosage is complicated.


Pay close attention to the amount of water the cat is drinking and how much is being eliminated through urine. In addition, look for vomiting and/or diarrhea along with weakness, disorientation, and lethargy. Laboratory tests will determine insulin requirements and oral medications. Frequent blood tests will be required after surgery, as well as an evaluation several times a year.




Nothing can be done to prevent this disease. But if your cat is diabetic, ask your veterinarian to check to see if Cushing’s disease is the cause.


Related Articles

Addison’s Disease in Cats

Hypoadrenocorticism is characterized by deficient production of glucocorticoids (cortisol) and/or mineralocorticoids (aldosterone).

Liver Disease in Cats

Copper storage hepatopathy is a condition caused by an abnormal accumulation of copper in the liver, which can lead to hepatitis and cirrhosis...