PrintHyperadrenocorticism in Cats
Cushing’s syndrome (hyperadrenocorticism) occurs when the adrenal gland produces too much cortisol. While cortisol is an essential hormone, elevated levels lead to illness. There are several possible causes to this disease, including a tumor in the pituitary gland or the outer layer of the adrenal gland. Although the disease is rare in cats, it is more likely to affect middle-aged or older cats and females more than males. Breed, however, does not seem to be a determining factor. In addition, diabetes almost always accompanies the ailment.
Symptoms
- Excessive urination (polyuria)
- Excessive thirst (polydipsia)
- Excessive eating (polyphagia)
- Weight loss or gain
- Enlarged liver (hepatomegaly)
- Fragile skin
- Symmetrical hair loss
- Diarrhea
- Vomiting
- Enlargement of the abdomen
- Curled ear tips
- Unkempt appearance
- Weakness (lethargy)
- Changes in sexual behavior
Causes
- Tumor in the pituitary gland
- Tumor in an adrenal gland
- Age of the cat
Diagnosis
The tests listed below may be used to determine the underlying cause of your pet's disease:
- Complete blood count (CBC)
- Chemistry analysis
- Urinalysis
- Blood pressure check
- X-rays of chest and abdomen
- Ultrasound (abdominal)
- Hormone tests
- Cortisol level tests
- MRI of the abdomen
polydipsia
A medical condition involving excessive thirst
polyphagia
Excessive eating or swallowing
polyuria
Excessive urination
pituitary gland
The gland that is found at the bottom of the brain whose job is to maintain appropriate levels of hormones in the blood
lethargy
The condition of being drowsy, listless, or weak
hepatomegaly
An enlargement of the liver to an abnormal size
insulin
A hormone created by the pancreas that helps to regulate the flow of glucose
adrenal gland
The gland that produces the hormone adrenaline and others; helps to regulate the metabolism, electrolytes, and even sexual function; also helps to regulate the way the body responds to injury, trauma, etc. The adrenal gland is found near the kidney. Also referred to as the suprarenal gland.