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Cardiogenic shock results from profound impairment of cardiac function, leading to a decrease in stroke volume (the amount of blood pumped out of each ventricle during contraction) and cardiac output, congestion of the veins, and narrowing of the blood vessels. Cardiac dysfunction may be caused by an enlarged or dilated heart muscle, compression of the lining of the heart, outflow obstructions, blood clot, severe heart disease, heartworm disease, or severe arrhythmias. Cardiac pump failure may also be secondary to a systemic disease which causes the myocardial layer (middle layer of the heart) to dysfunction, such as from blood poisoning. The result is low blood pressure and compromised blood flow in the tissues, with reduced tissue oxygen delivery.
Most causative conditions for cardiogenic shock are associated with markedly depressed left or right ventricle function, but other conditions that can cause cardiac compression and lead to inadequate filling of the ventricles may also play a role. Leaking from the pericardium – the sac enclosing the heart - or conditions that cause severe inflow or outflow obstruction to the ventricles are possible culprits. Low cardiac outflow can lead to severely low blood pressure, resulting in diminished blood flow to tissues. Further, reduced blood flow to the tissues causes organ ischemia (loss of blood to organs) and energy depletion, leading to abnormal organ function. Secondary organs that are affected include the brain, heart, lung, liver, and kidneys. As shock progresses, congestive heart failure may develop. Abnormal rises in left atrial pressure and pulmonary venous pressure may lead to fluid being trapped in the lungs. Any breed, age, or gender can be affected.
Primary Cardiac Disease
Secondary Cardiac Dysfunction
Because there are so many possible causes for this condition, your veterinarian will most likely use differential diagnosis. This process is guided by deeper inspection of the apparent outward symptoms, ruling out each of the more common causes until the correct disorder is settled upon and can be treated appropriately.
Blood pressure measurement will document low blood pressure, and electrocardiography may aid in the detection of arrhythmias. Pulse oximetry, a procedure using a device which measures oxygen saturation by fluctuations of light absorption in well-vascularized (supplied with blood) tissue during systole (contraction) and diastole (dilation) may reveal low blood pressure. Blood gas analysis may uncover metabolic acidosis, a decreased pH, and bicarbonate concentration in the body fluids, caused either by an accumulation of acids, or by abnormal losses of fixed base from the body, as in diarrhea or renal disease. A chest x-ray may reveal an enlarged heart or evidence of pulmonary edema (congestive heart failure). Echocardiography may document cardiomyopathy (disease of the heart muscle), disease of a heart valve, limited heart muscle contractability, or pericardial compression.
If the degree of cardiac dysfunction has progressed to a condition of shock, intensive hospitalized treatment will be necessary. Drainage of the pericardium is essential for patients displaying compression of the lining of the heart, and fluid therapy will be kept to a minimum until cardiac function is improved. This may be done with the use of positive inotropes, fluid or drug agents that alter the force or energy of muscular contractions; with vasodilators, which relax smooth muscles and widen blood vessels to improve flow; or by decompression of a pericardial (heart sac) leakage, as congestive heart failure may be exacerbated.
Cardiovascular monitoring will be conducted by electrocardiogram (ECG), which measures the electrical currents of the heart muscle, and measurement of central venous pressure and blood pressure is useful for determining the effectiveness of the given treatment. Oxygen supplementation is important, as with decreased blood flow, there is a concurrent decrease in oxygen reaching the tissues. Oxygen can be administered by oxygen cage, mask, or nasal tube. In addition, your veterinarian will choose any appropriate drugs to treat your cat's specific condition.
After the initial treatment, your veterinarian will want revisit your cat to monitor heart rate, pulse intensity, mucous membrane color, respiratory rate, lung sounds, urine output, mentation (mental activity), and rectal temperature.
Pertaining to the lungs
The sac of membranes that hold the heart
The number of respirations per minute; one respiration equals an inhalation and exhalation
The term used to refer to contraction of the ventricles of the heart
a) A cavity in certain animals b) Term refers to a rear chamber in the heart or a cavity in the brain
The term for the membrane around the heart
Something that is related to the whole body and not just one particular part or organ
A blood deficiency
The dilation of the ventricles of the heart
The amount of pressure applied by the blood on the arteries.
The widening of something
The collection of fluid in the tissue
A condition of the body in which pH levels are abnormally low.
A record of the activity of the myocardium
A special type of tissue that exudes mucus