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Manipulation of the tumor may result in the release of histamines from the tumor due to the mast cells releasing from the tumor into the blood stream. Antihistamines may be prescribed to alleviate some of the symptoms related to this effect. This same behavior can come into play as a result of surgical intervention; antihistamines will be used under the circumstances, as a large release of histamines on the body can have a drastic effect on the organs.
Surgery is the treatment of choice for mast cell tumors of the skin. Surgical removal of the spleen is the treatment of choice for mast cell tumors of the spleen. Surgical removal of the spleen along with chemotherapy may be beneficial when mast cells circulating in the blood accompany mast cell tumors of the spleen.
Excisional biopsy with wide margins is reasonable for very small tumors. Incisional biopsy of large mast cell tumors is recommended to obtain a tumor grade, to predict prognosis, and to establish a treatment plan. Your veterinarian will probably consider pretreatment with antihistamine therapy prior to an incisional biopsy. Biopsy of lymph nodes and other suspicious internal organs is appropriate. Complete surgical removal with 3-cm margins in all planes is recommended for all moderate Grade 2, high Grade 2, and Grade 3 tumors; margins of 2 cm or less may be adequate for Grade 1 and low Grade 2 tumors. Surgical removal of regional lymph nodes is recommended for all high Grade 2 and Grade 3 tumors.
Your veterinarian will want to microscopically evaluate any new masses and evaluate the lymph nodes at regular intervals in order to detect spread of Grade 2 or Grade 3 tumors. Your doctor will also want to perform a complete blood count at regular intervals if your cat is receiving chemotherapy. Immunity can be affected by cancer fighting drugs, so it will be important to protect your cat from illness and communicable diseases during this period, as well as sticking closely to a healthy, immune boosting diet.
The prediction of a disease’s outcome in advance
The area between the vulva and anus or scrotum and anus
The sac that holds the testes; may also be referred to as the scrotal sac
Found underneath the dermis
The genitalia of a female; found on the outside
The growth of pathogens away from the original site of the disease
Small structures that filter out the lymph and store lymphocytes
a) inhaling b) getting out fluid or gas by the act of sucking.
Not being able to cause harm; the opposite of malignant.
The process of removing tissue to examine it, usually for medical reasons.
The cutting of a piece of tissue or organ for medical examination
The end of the gastrointestinal tract; the opening at the end of the tract.