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Dr. Coates is a veterinarian based in the other “Sunshine State” – that's Colorado to the rest of you – where she lives and plays with a varied range of animals. She shares her professional and personal experiences, Monday through Friday, here on petMD's blog, the Fully Vetted. Log in for your daily dose of her insight and wisdom.

 

Histiocytoma: The benign canine tumor with a not-so-friendly look and feel

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September 23, 2008 / (28) comments


Both my French bulldogs have suffered from unsightly, often-itchy and technically benign tumors we call histiocytomas.  Though histiocytomas typically resolve after two to three months, the uncertainty of this tumor’s provenance leads most vets to snip it off (or at least part of it) to ensure its benignity.

A surgical scalpeling of a “benign” mass may sound extreme to you, but since histiocytomas can be both annoying and scary, surgery is often indicated.

Annoying: Because they often show up on the head and feet, places where a perfectly round, ulcerated mass can be scratched or licked at easily.

Scary: Because it’s hard to tell if what’s just popped up on your dog’s skin (and it usually happens fast) is a nasty mast cell tumor (or some other such monster mass)…or its more easy-going cousin, the histiocytoma.

While young dogs (under three years of age) are more likely to get these, they can happen to dogs of any age. Indeed, my older Frenchie, Sophie Sue got one about a year ago. She was nine—not exactly a spring chicken. Vincent has had three. And he’s not yet two years old.

Some breeds are more predisposed. Labrador retrievers and boxers, for example. Though Frenchies aren’t on the list, perhaps they should be… (Perhaps they should be on the list for almost everything if my recent round of healthcare scares is any guide.)

Ugly and prominently placed as they typically are, most owners want histiocytomas removed. Some vets, however, will counsel owners to either wait a few weeks (especially if the dog is young and statistically less likely to be suffering from a malignant mass) or to have a simple section of it snipped (with a local anesthetic) for histopathological analysis at the pathology lab.

Other vets will even take a needle poke at it, though most pathologists find that histiocytomas are not easily disgnosed definitively through this method (cytology).

If the dog is older or the mass is especially annoying to the dog or owner, however, we remove the whole sucker and clean up the mess quickly. Unfortunately, though, this approach is more costly and usually requires general anesthesia. It’s nonetheless the approach I take for more than half of these tumors…better to be safe than sorry, right?

Still, most owners need to know they have a choice. The nervous Nellies among you (like me) are less likely to want to stare at a mass for a couple of months to see if it simply goes away. The rational or more anesthetically cautious, however, are justified in waiting—as long as their dog is young and/or hasn’t suffered from malignant masses in the past.

Whatever choice you make, consider histiocytomas an excellent foray into the world of skin tumors. It’s like a warm-up for what’s likely to come as your dog ages. And it’s not all bad. Look on the bright side: Curing cancer is sometimes just a scalpel slice away.

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COMMENTS (28)
1
by Nina on 12/12/2009 01:40pm

My 17 year old shih tzu has a benign melanoma tumor on the weight bearing pad of her foot.  She's had one major operation which included using one of her toes to reconstruct the pad.  She's had 2 other removals under a local.  All of this within a year.  It came back again but there is not enough skin to remove it.  It is now very large.  I'm wondering if there is anything that anyone knows of that will shrink a tumor.  She's extremely healthy and could live another year or even more but not in pain.  I really need help.  I'm talking anything, herbs, vitamins, drugs. Thanks

2
by Kara on 12/10/2009 12:17am

Is it really possible that what looks like these single red bumps on your website could possibly be viral papilloma?  The bump that was taken off of my 9 year old poodle looked like a single mean looking red bump which the vet thought was a histocytoma or a mast cell tumor.  I am nervous that they do not have the right pathology report. 


signed,


concerned

by Sean Taylor on 04/30/2013 12:32am

I would like to suggest you use lavender essential oil on the tumor 3 times a day. Studies have shown it to shrink tumors with amazing speed. I can't promise it works because i have not had the need to test it up until now. Though i have recommended it to humans going undergoing treatment for cancer and from what i hear it seems to have effect. It certainly couldn't hurt to try right?

3
by KV on 11/02/2009 09:33pm

My 6 month old puppy (frenchton: french bulldog/boston terrier mix) formed a small red bump on top of her paw between her toes.  I took her to the vet today today; they told me she indeed has a histiocytoma as the website described.  I took her to the vet I've been taking her to for all of her shots, and they told me that it will have to be surgically removed for approx. $200.00 +, and that it woudn't go away on it's own.  So, I went to another vet and got a 2nd opinion.  She was prescribed Gentocin, which is a topical spray.  I was told that it should go away over time.  That we should try this before we do surgery.  I'm going to see how that works, it doesn't seem to bother her much.  I think I may have just switched vets, the second vet seemed must more caring, and realistic.  

4
by lizzy on 07/23/2009 07:58pm

I have a 10 month old dog, and about a month ago he developed what looked to be a wart-like growth. It doesn't seem to bother him at all, unless you squeeze it fairly hard. It hasn't grown at all, but it also hasn't gone away. It's about 3 cm in diameter, and perfectly dome-shaped. I was wondering what the best thing to do about this was? I see that it's fairly common for dogs to have these, but it's quite unsightly. Is there any at home way to remove it? Or will it go away on its own? Please help!! He only has one, and I'm not too worried that it's cancerous or anything, but wouuld like it better if he didn't have it!!

5
by Jane on 03/30/2009 06:13pm

My 6 year old mixed-breed (border collie? Nova Scotia Toller?) developed a growth on his tail a month or so ago.
I decided to keep an eye on it...and a few days ago was distressed to discover part of it had broken off and was caught in his tail fur. That part was hard as a rock, gray on the outside, black around the edges.
The remaining part is the size of two peas, is angry looking and is gray, with black and goldish speckles on the end where it broke off. It seems to be attached with blood vessels (it's pinkish where it joins his tail). We have a vet apppointment tomorrow -- with a new vet; our vet of 30 yars just retired.. What might I expect? It hurts him only if I touch it to examine it.

6
by Liz on 03/28/2009 08:15pm

I'm so glad to have found this page. My dog started lickiing his paw like crazy last night, I thought maybe he had a cut or something, and found a pink lump just like the one pictured. I went to the vet today, and by now the lump was bright red from his licking. The vet said it looked "suspicious"...needless to say that was enough to make me nearly hysterical. She's talking about cutting off his leg etc. She did the aspiration, and I will find out by Wed. Meanwhile, my friend came over looked at it, and said it is exactly what her lab had, in almost the same spot. Her vet scared her also, stating the same scenario. I'm just curious, why don't the vets recognize this as a histiocytoma, and say well this is what it looks like, instead of scaring us to death??

7
by Lolita on 03/14/2009 01:35am

My flat-coated retriever who is 3 got a tumorin her paw about 2 months ago. Various vets say it's a histiocytoma and we should wait for it to go away on its own. However, it's starting to take over her paw and it varies in size every day. We recently started feeding her no-cereal/grain food called "Origen". Is there anything we could do to: a. speed up the healing process b. make her stronger c.make the cuts on the tumor heal. d.reduce pain or stress?

8
by Angela on 03/04/2009 01:25pm

Our 21 month old Border Collie had a pink patch appear under his top lip a few weeks ago - it has now grown into a lump and has increased to the size of a large pea over the past two weeks. The vet suspects histiocytoma and put the dog on steriods to shrink the lump - it hasn't worked so has suggested an operation to remove to be on the safe side. We don't want to put our dog through an op if unnecessary - but are scared if we leave it, it may be something which will spread into his system. What a dilemma!

9
by John Wagonis on 02/28/2009 08:02am

Our 34 month old Pug just developed a perfectly round and evenly domed very smooth medium pink mass between his right eye and nose. It is on one of his wrinkles. Vet though it might be fungus at first and we tried a topical treatment. No resolve. The mass grew to approx. 5 or 6mm in diameter. And it is a smooth pink color, not bright red or crusty like most of the photos I am seeing on-line. We just had it removed on Wednesday. It took over a full day for the anesthesia to wear off, we thought something was wrong with him. But he became more chipper by 7 PM the evening following his surgery. Yesterday he bahaved as normal as if nothing had happened. Then on his walk this morning, I noticed a sliver of new growth immediately adjacent to the growth that was just removed. We are uncertain of what it is, unless a piece of it was missed and it is rejuvenating itself. We will watch it Sat. and Sun. and call our vet on Monday. Our vet felt certain it was not cancerous, so we went with his belief and did not do a biopsy. If this new growth might just be inflamed skin or the sutcher dislodging, then we will try to keep it clean. If it is a leftover piece of tumor that doesn't want to go away, then we are very concerned. Has anyone else encounter something similar?

10
by Susie on 02/22/2009 11:49pm

My 13 month old Dogue De Bordeaux developed a raised black spot on the inside of her ear flap 2 weeks ago and now it's the size of a half of a green pea. It doesn't seem to itch or bother her. Its dark and rough and feels solid. This website is the closest I've gotten to a description of what is on her ear. At first I thought it might have been a big tick, but we don't have ticks in Las Vegas. After reading your experiences I plan to get an appointment at a Vet. Dermatologist tomorrow (she also has other skin disorders around her breasts). The poor, sweet little girl dog has had so many vet trips since I got her (mainly opthamology) that its a real ordeal for me to get her out of the car. She represents everything one can expect from a puppy mill, pet shop or backyard breeder.(I am now older and wiser) I paid a LOT for this Dogue and so far, even more for vet bills, but I love her and will do whatever it takes to keep her healthy. I suspect she has an immune disorder.

11
by Fawn on 01/30/2009 08:49pm

My Wolfdog is 15 years old and had a small round purplish circle on his paw for almost 2 years, the vet had looked at it and said it was normal for older dogs to get them. Overnight it blew up into a huge perfectly round red tumor.  I took him to the vet who just gave him antibiotics and said he didn't want to put him under to take it off because of his age.  The next day I thought, why can't they just freeze it off or deaden it like a dentist does?  The vet said that he had never thought of that!  So I have been searching for 10 days to find a vet in Los Angeles that can do that and there is NO ONE.  So I am going to another vet tomorrow for them to put a needle in it and try to extract some of the cells to see if it's cancerous or not.  His paw is a little swollen today and I am worried.  My 20 year old American Eskimo almost died 3 weeks ago and is doing better (waggin tail, smiling and eating constantly now), so I really don't need this happening now too!  My Wolf's tomor looks similar to the photos on this page, but more pale in color. Anyway, Thanks for listening.

12
by Sher on 01/22/2009 11:30am

My 5 year old black lab mix developed a round, pink, hairless bump on her muzzle in the whisker area a week ago, and I have noticed that it is growing. She has
skin allergies/hot spots in the summer that virtually go away in the winter. In the last few months she has developed two black, pea sized abcesses on her trunk that ruptured and then healed nicely. With the economy and our finances the way they are now, I can not afford a large vet bill, unless it's very necessary. What do you recommend? Thanks.

13
by karen on 01/21/2009 07:00pm

my 11 year old greyhound had a mass removed last week it grow so quick i was prepared fopr the worst.went back today for resulte to find out it was not malignant..how relieved were we.

14
by Deb on 12/14/2008 02:08pm

My 2 year (almost 3 year) old yellow lab developed a red lump on her bottom lip about 3 weeks ago.  The vet did a needle aspiration and cytology reporting that it was a histiocytoma.  I opted to have it surgically removed and sent away for a pathology report.  I still have not gotten the results of the pathology report.  2 weeks after the surgery another one has popped up under her eye.  Is this a bad sign?  Does this mean that it is spreading?  I have never experienced anything like this with any of my other dogs, and I'm extremely nervous and worried that this is cancerous.


 

15
by melanie on 11/10/2008 09:31pm

My 11-year old yellow lab, Fred developed a very scary red growth over the past few days.  (it just used to be a small pinkinsh bump, that our vet previously examined and determined non-threatening) It seems to bother him as he has been rubbing his paw on it making it inflamed and bright red.  I decided to go out and get one of those neck coller things to stop him from messing w/ it. Is there anything else I can do as maureen asked in the post above on 10/2/08? Thanks.

16
by melanie on 11/10/2008 09:29pm

My 11-year old yellow lab, Fred developed a very scary red growth over the past few days.  (it just used to be a small pinkinsh bump, that our vet priously examined and determined non-threatening) It seems to bother him as he has been rubbing his paw on it making it inflamed and bright red.  I decided to go out and get one of those neck coller things to stop him from messing w/ it. Is there anything else I can do as maureen asked in the post above on 10/2/08? Thanks.

17
by maureen on 10/02/2008 08:20pm

My 5-month-old mixed breed was just diagnosed with histiocytoma on her head over her eye. It has grown so large in the last couple of days and is very ugly and oozing. Is there something I can put on it to speed up the healing? The vet said to just wait at least a month since she is so young and it doesn't bother her at all. Thaanks for the info

18
by parlance on 10/02/2008 09:34am

Thanks, Dr K.
Even knowing the word histiocytoma gives me a handle on how to think about the situation if it crops up again.
Blogs like yours empower us laypeople.

19
by Dr. Patty Khuly on 09/29/2008 06:00pm

parlance: More than likely, it was nothing (something inflammatory or infectious and nothing more). But there's no way of knowing without taking it off--not that I'm advocating you do so at this point if it's almost gone. From the sound of it it might well have been a histiocytoma.

20
by parlance on 09/28/2008 09:57am

Thanks for the wonderful info you post. I read all your posts but don't comment. However, I'd like to just ask something about this one. My dog had a lump on her head and the vet was going to take it off but said not to rush as it looked okay. Now it's virtually gone - it's just a tiny lump. Does that mean it was okay?

21
by Barbara A. Albright/New Hampshire on 09/24/2008 06:55pm

Dr. K: Thanks for answering that, they are so bizarre in appearance & location! I remember feeling wierd ,after the first couple of dogs, thinking it was some kind of herpes!

My youngest Sealy got one on the back of a hock, that was just a mess entwined in hair, serious scissor surgery and patience to remove the deflated mess without taking her skin with it.

And have mentioned 2 melanomas, and a weird plasmacytoma with my now 11 yr. old, she was 8 and it was right next to her nose. At first it appeared like a histiocytoma, but had a different textured surface. Hope that one wasn't meant to be bad news.

22
by Dr. Patty Khuly on 09/24/2008 12:05pm

K.H.: Black masses may be very nasty melanomas or mast cell tumors--or they may be warts or skin tags. Some vets want to biopsy them all--just in case. Other vets take one look and opt to leave them--unless they begin to change (bleed, ulcerate, grow broad at the base, etc.). Hope that helps.

23
by Dr. Patty Khuly on 09/24/2008 12:02pm

Barbara: Good question. They emerge from a cell called a Langerhans Cell. These are cells involved in the immune functions of the skin. As with many cancers, they seem to become deregulated. In this case it's more like temporary immunological insanity. It's neighbors eventually come by to clean up the mess. Too bad it takes 2-3 months for that to happen.

24
by K.H. on 09/24/2008 11:25am

The 'bumps'/tumors shown here are red - how are they different - if they are - from black ones? My dog seem to get small, black, lumpy ones that my vet doesn't think are a problem. I 've had some of them removed anyway because of placement on ear or muzzle (he was having a dental anyway), although I didn't have them biopsied. Should I have?

25
by Barbara A. Albright/New Hampshire on 09/23/2008 08:14pm

Every single dog I have had has gotten one, as early as 7 mos. to as old as nine years of age. I had one surgically removed, but waited the rest out. Ugly things.

What on earth causes them?

26
by Elizabeth - from Nova Scotia on 09/23/2008 04:14pm

I went through this last January with my then 7 yr old male Labrador. It came very fast, two days before Christmas it wasn't there ( I have pictures to prove it) and then Jan 1st he suddenly had a red bump on his lip, the next day it tripled in size. My vet looked at it on a Monday and by Thursday when he was scheduled to have it removed I found another one that wasn't there when my Vet examined him. My vet and I decided to remove them both. She got good margins just in case. I am one of those nervous nellies but considering his age I was not willing to take any chances on it being a mast cell tumor. Better safe than sorry.

27
red itchy growing bump
by Silka Love on 10/28/2012 12:20pm

my 4 month puppy a spanial/poodle mix has a red bump on her thigh that has gotten bigger over the past few days. It's hard and round i tried to pop it with a needle because i thought it was a blister. She didnt feel the poke at all and it had no liquid inside its a mass.it worries me because she nibbles on it.I've been reading the posts and feel a little better because ii thought she had cancer. will the bump get worse since i poked it? and what should so that she wont bite it? should i put peroxide or neosporin on it?

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About fully vetted

Patty Khuly, VMD, MBA

Photo of Dr Khuly

Dr. Khuly is a former petMD blogger and small animal veterinarian in Miami, Florida, where she practices medicine at Sunset Animal Clinic and serves on the board of the South Florida Veterinary Medical Association. She is a graduate of Wellesley College, the University of Pennsylvania School of Veterinary Medicine, and The Wharton School of Business.

As a significant sideline, she writes...a lot. She authors pet health columns for USA Today, The Miami Herald and Vetstreet. She also writes a popular monthly column for Veterinary Practice News and serves as regular contributor to Veterinary Economics, The Bark, and the Veterinary News Network.

Dr. Khuly lives in South Miami with her brood of hens, goats, dogs, cats...and humans.

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