Dr. Coates is a veterinarian based in the other “Sunshine State” – that's Colorado to the rest of you – where she lives and plays with a varied range of animals. She shares her professional and personal experiences, Monday through Friday, here on petMD's blog, the Fully Vetted. Log in for your daily dose of her insight and wisdom.

 

Rabies vaccines every year? Seriously?

August 06, 2009 / (8) comments


Here’s a question I often get: Why do pets have to be vaccinated every year for rabies? Is there really a medical reason for this, or is this regulatory overreaching at the expense of our pets?


After all, humans are often vaccinated only once for certain "bugs" and remain immune to the particular disease they cause for life. Why is it not the same for animals?

The main reason people ask this is because they’ve heard or read of negative reactions to rabies vaccines in some pets. They assume this product is less safe than they’re led to believe by veterinarians and regulatory agencies, and they’re worried for their pets––particularly those who might suffer from chronic conditions or at very low risk of actually coming across a rabies infected animal.

Truth be told, rabies vaccines are considered very safe. Nonetheless, the reality is uncomfortable: more pets actually die of the consequences of being vaccinated than come down with the virus.

Having said that, you might wonder how it’s possible for me, or any veterinarian, to defend the use of this vaccine. But if you think about it, this scary-sounding reality is likely the case with all successful vaccines. After all, the goal of a vaccine is to render a disease so rare that very few animals are ever even exposed to it.

For example: The side-effects of polio vaccination in humans are far more common than the disease itself. And yet we’d never advocate the elimination of the vaccine from our medical repertoire. That’s because the vaccine has managed to keep polio out of our population so successfully. Vaccination is therefore considered an "acceptable risk" to the individual, given the population’s overall protection.

Similarly, it remains the consensus of the human and veterinary medical communities alike that the benefits rabies vaccine confers to both human and animal populations outweigh the individual risk of vaccination.

On the plus side, yearly vaccination is no longer considered a medical necessity. Every three years is now considered sufficient. And this less stringent recommendation may well relax even more in years to come.

Consider, also, that while our government may require rabies vaccines every three years for the protection of public health, individual veterinarians may exempt some pets––temporarily, at least––on the basis of their compromised health.

It's also the case that testing for the presence of rabies antibodies with a simple blood test called a "rabies titer" is one approach to achieving exemption from additional, potentially unnecessary doses of vaccines in other countries. The U.S. does not yet recognize this test when it comes to replacing the requirement for vaccination.

That’s because the duration of immunity of rabies vaccination has not been completely and irrefutably established by the veterinary community. It’s also because measuring antibody levels through blood testing does not necessarily mean the animal is 100 percent immune to rabies. (Something called "cell immunity" is arguably as or more important than the number of antibodies the immune system brings to bear.)

Yes, it’s true that if your pet has already received a round or two of rabies vaccines, he or she is likely to be protected by antibodies against rabies for his or her entire lifetime. In fact, I received the human version of the rabies vaccine in 1991 and my own antibody levels are still quite high. So why force pets to undergo such frequent vaccines? Are they so biologically different?

Not at all. But you might choose to view things differently if your child were bitten by an animal that had been vaccinated only once ... ten years ago, for instance. In the absence of hard science on the subject, human health will always trump animal health in these matters.

Until veterinary science can prove that vaccines last longer than they do, your best bet in the interim is to play it as safe as you can. Make make sure your pet is healthy when vaccinated and only receives his or her rabies shot when administered by a trusted veterinarian whose selection, storage, and handling of the vaccine is likely to adhere to the highest standards of vaccine quality and safety.

 

Dr. Patty Khuly

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COMMENTS (8)
1
Why are rabies vaccines still required every year in some places
by Stacy Smith on 08/06/2009 01:57pm

More importantly, how can we get municipalities to change their requirements?

Where we live our pets are still required to have a rabies vaccine every year and vets are thrilled. I've heard from several that they don't want the statute to change because it would mean seeing clients less often and result in a drop in revenue.

Seems like we're between a rock and a hard spot.

2
Rabies Vaccines
by Lucy De Andrade on 08/06/2009 02:20pm

Speaking of the possible longer lasting duration of the rabies vaccine in pets, couldn't a titer test be run after 3 years are up & check to see, if & how much protection still remains?

3
To Stacy
by Dr. Patty Khuly on 08/06/2009 02:38pm

Unfortunately, that's up to the municipal public health and animal services in your neck of the woods. What veterinarians want in any given region should not dictate care. Science should. And the science is clear. The AVMA, AAHA and loads of other veterinary professional organizations have explained 'till they're blue in the face that laws requiring yearly vaccination are not keeping anyone safer. Now it's up to people like you to bring it up with your municipal leaders, animal services and/or public health administrators.

4
On Titers
by Dr. Patty Khuly on 08/06/2009 02:41pm

Lucy: We used to think titers would be good enough but, unfortunately, they're not as foolproof a method as we would like. We rely on the official history of vaccination because we're 100% positive that the immunity lasts at least three years. We don't know that titers equal 100% immunity. Hope that explains things.

5
Rabies Challenge Study
by Susan Gross on 08/09/2009 10:55am

Drs. Jean Dodd and Ronald Schultz are working on the Rabies Challenge Study to test the duration of immunity of the rabies. The goal of the study is to push back the required interval of rabies vaccination. This is a non-profit study and is being funded mainly by donation. Check out the web-site at http://www.rabieschallengefund.org/ and donate if possible. I did.

6
Thanks
by Teresa on 02/01/2010 09:23pm

I love your blog - thanks for this info on rabies vacc. I had to jump over to a different vet than my regular one to get a 3-yr. rabies vaccination for my fuzzy boy this year, on the recommendation of his specialist (he's 12 1/2 - my dog, not the vet!). It was a bit odd going back to my regular vet - for whom I worked many years ago - and telling him I didn't want the yearly vaccine anymore, but having it come on recommendation of the specialist HE recommended did a lot to bolster my confidence. The vet from whom I got the 3-yr. rabies vacc, whom I also like, did not have the non-annual DHLPP, so I still had to get the 1-year type. I'd like to check around next time for the longer-lasting one, but it's going to get a bit ridiculous with the separate exam fees soon!

7
rabies challenge fund
by Sarah F. on 07/18/2010 03:47am

Not to open a can of worms, but I'm not entirely impressed with the approach used by the rabies challenge fund. The irony is that in theory, I support what they're doing. It makes sense to me that more data are needed in the form of challenge studies to show that pets are protected for longer than the product labeling would indicate. I also accept that there are rarely serious adverse events with vaccines.

In practice, however, they make their plug by overstating the risks of vaccination (particularly in regard to fibrosarcoma in dogs), and I'm concerned that will lead to public fear of vaccinating and mistrust of vets who follow a conservative vaccination schedule. I hope it doesn't lead to mistrust of vets in general. Their website claims behavioral adverse effects of rabies vaccination have been "documented," including "aggression and separation anxiety; obsessive behavior, self-mutilation, tail chewing; pica - eating wood, stones, earth, stool; destructive behavior, shredding bedding." These are things many dogs do. I would like to see placebo-controlled trials demonstrating an excess of these supposed adverse effects in dogs who had received vaccine over and above the population base rate. I'm skeptical that this is unscientific nonsense, but if they can show controlled trials, I'd be open to revising my position.

They also overstate, in my opinion, the strength of the existing data as to longer durations of immunity. From what I can tell, the existing data are suggestive, but do not unequivocally demonstrate, long durations of immunity such as 5+ years or lifetime protection (after all, that's why they want money for research, because the data we have now are not sufficient). Their posting on a pet owner forum I am a member of seemed to suggest that these longer durations of immunity were a fact, rather than a hypothesis.

Bottom line: I'm fairly convinced that rabies vaccination is generally safe, and would rather see dogs overvaccinated than undervaccinated given the human risks. I do support continued research that might provide data to justify longer intervals between boosters. I do not wish to see the public unnecessarily frightened about vaccination.

8
P.S. re challenge fund
by Sarah F. on 07/18/2010 06:28pm

FYI, I am not a veterinary professional, just a concerned owner with some scientific background.

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About fully vetted

Jennifer Coates, DVM

Photo of Dr Coates

Image credit: Jim Piraino

...graduated with honors from the Virginia-Maryland Regional College of Veterinary Medicine in 1999. In the years since, she has practiced veterinary medicine in Virginia, Wyoming, and Colorado. She is the author of several books about veterinary medicine and animal care, including the Dictionary of Veterinary Terms: Vet-Speak Deciphered for the Non-Veterinarian. Dr. Coates also writes short stories that focus on the strength and importance of the human-animal bond, and freelance articles relating to a variety of animal care and veterinary topics. Dr. Coates lives in Fort Collins, Colorado with her husband, daughter, and various species of pets.

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