Q. My 45lb husky is already on 40mg daily of Fluoxetine for separation anxiety. It worked for several months, but now her anxiety is very bad again.
DAVID ELBEZE, DVM, MRCVS
A. Your dog is on the highest dose already so I would not recommend giving more than this. You can try supplements like valerian, zylkene and adaptil but it sounds like a bad case and i'm not sure these will do much.
I recommend going to your vet and possibly ask for additional meds, maybe a benzodiazepin (xanax, diazepam). It will make him sleepy but hopefully will help with the condition.